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Segment Information (Tables)

9 Months Ended

Sep. 30, 2025

Segment Reporting [Abstract]

Schedule of Segment Reporting Information, by Segment

The following table illustrates information about segment revenues, significant segment expenses, and segment net income (loss) for the three and nine months ended September 30, 2025 and 2024 (in thousands):

			Three Months Ended September 30,												Nine Months Ended September 30,
			2025						2024						2025						2024
Revenues			$	159,395					$	117,085					$	468,282					$	319,178
Less1:
Cost of product sales			2,187						3,211						9,553						6,175
Research and development
Berotralstat			2,575						2,954						9,214						10,504
BCX17725			7,574						1,154						13,346						6,591
Avoralstat			1,800						2,104						7,584						4,960
Factor D Program			35						1,193						454						7,299
Research, discovery and preclinical programs			5,457						3,309						11,641						8,325
Compensation and related personnel costs			13,313						14,257						38,025						42,630
Stock-based compensation			6,520						8,530						24,374						20,923
Other non-program specific and indirect costs			7,329						7,580						20,621						23,965
Selling, general and administrative			83,014						65,101						252,866						185,841
Interest income			(2,238)						(3,591)						(7,778)						(11,176)
Interest expense			19,661						24,828						64,737						74,067
Foreign currency (gains) losses, net			(35)						(98)						27						37
Loss on extinguishment of debt			2,740						—						6,911						—
Other income			(2,667)						—						(2,667)						—
Income tax (benefit) expense			(769)						586						1,358						1,123
Segment net income (loss)			12,899						(14,033)						18,016						(62,086)
Reconciliation of segment profit or loss:
Adjustments and reconciling items			—						—						—						—
Consolidated net income (loss)			$	12,899					$	(14,033)					$	18,016					$	(62,086)
1 The significant expense categories and amounts align with the segment-level information that is regularly provided to the CODM.

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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X

- References

No definition available.

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