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Significant Accounting Policies and Concentrations of Risk (Details)
shares in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
USD ($)
Sep. 30, 2024
Sep. 30, 2025
USD ($)
segment
shares
Sep. 30, 2024
USD ($)
shares
Dec. 31, 2024
USD ($)
Significant Accounting Policies and Concentration of Risk [Line Items]          
Number of reportable segments | segment     1    
Number of operating segments | segment     1    
Birmingham lease restricted cash $ 1,979,000   $ 1,979,000   $ 1,610,000
Long-term investment maturity, minimum (in years)     12 months    
Antidilutive securities excluded from computation of earnings per share, amount (in shares) | shares     22,191 44,441  
Reclassification from accumulated other comprehensive income, current period, before tax     $ 0 $ 0  
Revenue Benchmark | Product Concentration Risk | ORLADEYO          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Revenue percentage 88.00% 88.00% 86.00% 88.00%  
Computer Equipment          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Property, plant and equipment, useful life (in years) 3 years   3 years    
Laboratory Equipment, Office Equipment and Software          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Property, plant and equipment, useful life (in years) 5 years   5 years    
Furniture and Fixtures          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Property, plant and equipment, useful life (in years) 5 years   5 years    
Maximum          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Maturity period of high quality marketable securities (in years)     2 years    
Average maturity period of high quality marketable securities (in months)     12 months    
Maturity period of short term investment (in months)     12 months    
Collateral for Credit          
Significant Accounting Policies and Concentration of Risk [Line Items]          
Birmingham lease restricted cash $ 1,400,000   $ 1,400,000   $ 1,400,000