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Subsequent Event (Details) $ / shares in Units, $ in Thousands					9 Months Ended
	Oct. 14, 2025 USD ($) $ / shares	Oct. 08, 2025 USD ($)	Jul. 24, 2025 USD ($)	Apr. 18, 2025 USD ($)	Sep. 30, 2025 USD ($)	Sep. 30, 2024 USD ($)	Oct. 01, 2025 USD ($)
Subsequent Event [Line Items]
Prepayment premium and fees on Pharmakon term loan					$ 3,802	$ 0
Pharmakon Advisors, LP | Line of Credit
Subsequent Event [Line Items]
Prepayment premium and fees on Pharmakon term loan			$ 50,000	$ 75,000
Prepayment premium			1,500	2,250
Interest expense			$ 376	$ 424
Disposal Group, Held-for-Sale, Not Discontinued Operations | BioCryst Ireland | Forecast
Subsequent Event [Line Items]
Upfront consideration to be received							$ 250,000
Contingent consideration to be received							14,000
Royalty release fee							$ 15,000
Subsequent Event | Astria
Subsequent Event [Line Items]
Conversion ratio	0.59
Price per share (in usd per share) | $ / shares	$ 8.55
Subsequent Event | Pharmakon Advisors, LP | Line of Credit
Subsequent Event [Line Items]
Prepayment premium and fees on Pharmakon term loan		$ 198,704
Prepayment premium		5,961
Interest expense		$ 485
Subsequent Event | Blackstone | Line of Credit | Secured Debt
Subsequent Event [Line Items]
Debt instrument, face amount	$ 550
Proceeds from issuance of long-term debt	350
Maximum aggregate principal amount	50
Subsequent Event | Blackstone | Line of Credit | Unsecured Debt
Subsequent Event [Line Items]
Maximum aggregate principal amount	$ 150

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