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Segment Information - Segment Reporting Information by Segment (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Sep. 30, 2025
Sep. 30, 2024
Segment Reporting Information [Line Items]                
Revenues $ 159,395     $ 117,085     $ 468,282 $ 319,178
Segment Reconciliation [Abstract]                
Cost of product sales 2,187     3,211     9,553 6,175
Research and development 44,603     41,081     125,259 125,197
Selling, general and administrative 83,014     65,101     252,866 185,841
Interest expense 19,661     24,828     64,737 74,067
Loss on extinguishment of debt 2,740     0     6,911 0
Other income 2,667     0     2,667 0
Income Tax Expense (Benefit) (769)     586     1,358 1,123
Net income (loss) 12,899 $ 5,085 $ 32 (14,033) $ (12,674) $ (35,379) 18,016 (62,086)
Reportable Segment                
Segment Reporting Information [Line Items]                
Revenues 159,395     117,085     468,282 319,178
Segment Reconciliation [Abstract]                
Cost of product sales 2,187     3,211     9,553 6,175
Selling, general and administrative 83,014     65,101     252,866 185,841
Interest income (2,238)     (3,591)     (7,778) (11,176)
Interest expense 19,661     24,828     64,737 74,067
Foreign currency (gains) losses, net (35)     (98)     27 37
Loss on extinguishment of debt 2,740     0     6,911 0
Other income 2,667     0     2,667 0
Income Tax Expense (Benefit) (769)     586     1,358 1,123
Net income (loss) 12,899     (14,033)     18,016 (62,086)
Adjustments and reconciling items 0     0     0 0
Reportable Segment | Berotralstat                
Segment Reconciliation [Abstract]                
Research and development 2,575     2,954     9,214 10,504
Reportable Segment | BCX17725                
Segment Reconciliation [Abstract]                
Research and development 7,574     1,154     13,346 6,591
Reportable Segment | Avoralstat                
Segment Reconciliation [Abstract]                
Research and development 1,800     2,104     7,584 4,960
Reportable Segment | Factor D Program                
Segment Reconciliation [Abstract]                
Research and development 35     1,193     454 7,299
Reportable Segment | Research, discovery and preclinical programs                
Segment Reconciliation [Abstract]                
Research and development 5,457     3,309     11,641 8,325
Reportable Segment | Compensation and related personnel costs                
Segment Reconciliation [Abstract]                
Research and development 13,313     14,257     38,025 42,630
Reportable Segment | Stock-based compensation                
Segment Reconciliation [Abstract]                
Research and development 6,520     8,530     24,374 20,923
Reportable Segment | Other non-program specific and indirect costs                
Segment Reconciliation [Abstract]                
Research and development $ 7,329     $ 7,580     $ 20,621 $ 23,965