    <SEC-DOCUMENT>0001140361-25-024089-index.html : 20250630
    <SEC-HEADER>0001140361-25-024089.hdr.sgml : 20250630
    <ACCEPTANCE-DATETIME>20250630073757
    ACCESSION NUMBER:		0001140361-25-024089
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		13
    CONFORMED PERIOD OF REPORT:	20250627
    ITEM INFORMATION:		Entry into a Material Definitive Agreement
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20250630
    DATE AS OF CHANGE:		20250630

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			BIOCRYST PHARMACEUTICALS INC
    		CENTRAL INDEX KEY:			0000882796
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				621413174
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-23186
    		FILM NUMBER:		251088764

    	BUSINESS ADDRESS:
    		STREET 1:		4505 EMPEROR BOULEVARD
    		STREET 2:		SUITE 200
    		CITY:			DURHAM
    		STATE:			NC
    		ZIP:			27703
    		BUSINESS PHONE:		919-859-1302

    	MAIL ADDRESS:
    		STREET 1:		4505 EMPEROR BOULEVARD
    		STREET 2:		SUITE 200
    		CITY:			DURHAM
    		STATE:			NC
    		ZIP:			27703
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>ef20051351_8k.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: ef20051351_8k.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-2.1
    <SEQUENCE>2
    <FILENAME>ef20051351_ex2-1.htm
    <DESCRIPTION>EXHIBIT 2.1
    <TEXT>
    Document 2 - file: ef20051351_ex2-1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.SCH
    <SEQUENCE>3
    <FILENAME>bcrx-20250627.xsd
    <DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA
    <TEXT>
    Document 3 - file: bcrx-20250627.xsd

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.LAB
    <SEQUENCE>4
    <FILENAME>bcrx-20250627_lab.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE
    <TEXT>
    Document 4 - file: bcrx-20250627_lab.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.PRE
    <SEQUENCE>5
    <FILENAME>bcrx-20250627_pre.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE
    <TEXT>
    Document 5 - file: bcrx-20250627_pre.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>7
    <FILENAME>R1.htm
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 7 - file: R1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>8
    <FILENAME>Show.js
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 8 - file: Show.js

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>9
    <FILENAME>report.css
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 9 - file: report.css

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>11
    <FILENAME>FilingSummary.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 11 - file: FilingSummary.html

    Document 11 - RAW XML: FilingSummary.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>JSON
    <SEQUENCE>13
    <FILENAME>MetaLinks.json
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 13 - file: MetaLinks.json

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>ZIP
    <SEQUENCE>14
    <FILENAME>0001140361-25-024089-xbrl.zip
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 14 - file: 0001140361-25-024089-xbrl.zip

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>15
    <FILENAME>ef20051351_8k_htm.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 15 - file: ef20051351_8k_htm.html

    Document 15 - RAW XML: ef20051351_8k_htm.xml

    </DOCUMENT>
    </SEC-DOCUMENT>