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v3.21.2

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2019
Cash flows from operating activities |  |  |
Net loss | $ (152,098) | $ (139,931) | $ (107,669)
Adjustments to reconcile net loss to net cash used in operating activities |  |  |
Depreciation and amortization | 9,750 | 6,677 | 6,111
Non-cash lease expense | 2,243 | (1,043) |
Loss on disposal of property and equipment | 2 |  | 189
Stock-based compensation | 36,998 | 17,096 | 11,170
Discount (premium) accretion on investment securities | 593 | (214) | (1,249)
Realized gain on investments | (5) |  |
Allowance for doubtful accounts | 40 |  |
Change in fair value of contingent consideration and indemnity holdback | (534) |  |
Non-cash interest expense | 67 | 152 | 233
Amortization of debt discount | 81 | 184 | 282
Changes in assets and liabilities: |  |  |
Accounts receivable, net | (2,202) | (14,272) | (6,685)
Inventories | (19,489) | (4,956) | (1,302)
Prepaid expenses and other current assets | (2,058) | (3,683) | 746
Other non-current assets | (4,653) | (554) | (2,064)
Accounts payable | 8,542 | (5,506) | 3,278
Accrued expenses | 3,115 | (2,648) | 4,210
Accrued compensation | 7,392 | 4,465 | 5,060
Other liabilities | (28) | 1,978 | (247)
Net cash used in operating activities | (112,244) | (142,255) | (87,937)
Cash flows from investing activities |  |  |
Purchases of property and equipment | (27,061) | (9,868) | (14,757)
Proceeds from sale of property and equipment |  |  | 21
Business acquisition, net of cash acquired | (483) |  |
Purchases of investments | (58,795) | (202,882) | (177,574)
Proceeds from maturity of investments | 242,494 | 98,100 | 87,500
Net cash provided by (used in) investing activities | 156,155 | (114,650) | (104,810)
Cash flows from financing activities |  |  |
Proceeds from exercise of stock options | 14,559 | 10,495 | 2,170
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses | 323,861 | 295,563 | 156,208
Proceeds from issuance under employee stock purchase plan | 4,944 | 3,428 | 2,700
Repayments of long-term debt | (3,333) | (3,333) | (2,500)
Repurchases of common stock for income tax withholding | (10,849) | (2,421) |
Net cash provided by financing activities | 329,182 | 303,732 | 158,578
Effect of exchange rates on cash, cash equivalents and restricted cash | 20 | 21 | 30
Net increase (decrease) in cash, cash equivalents and restricted cash | 373,113 | 46,848 | (34,139)
Cash, cash equivalents, and restricted cash at beginning of year | 94,246 | 47,398 | 81,537
Cash, cash equivalents, and restricted cash at end of year | 467,359 | 94,246 | 47,398
Supplemental disclosure of cash flow information |  |  |
Interest paid | 167 | 438 | 779
Income taxes paid, net of refunds | 101 | 172 | 291
Non-cash investing and financing activities |  |  |
Property and equipment additions included in accrued expenses and accounts payable | 2,011 | 1,333 | 170
Operating lease right-of-use assets obtained in exchange for operating lease liabilities | 33,617 | $ 3,718 |
Conversion of redeemable convertible preferred stock warrant liability to equity |  |  | 631
Conversion of redeemable convertible preferred stock to common stock |  |  | $ 290,462
Issuance of common stock in connection with the iGenomX acquisition | $ 26,773 |  |

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