<SEC-DOCUMENT>0001104659-22-017130-index.html : 20220209
<SEC-HEADER>0001104659-22-017130.hdr.sgml : 20220209
<ACCEPTANCE-DATETIME>20220209163901
ACCESSION NUMBER:		0001104659-22-017130
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20220209
DATE AS OF CHANGE:		20220209

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Twist Bioscience Corp
		CENTRAL INDEX KEY:			0001581280
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				462058888
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-238906
		FILM NUMBER:		22607778

	BUSINESS ADDRESS:	
		STREET 1:		681 GATEWAY BLVD.
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		800-719-0671

	MAIL ADDRESS:	
		STREET 1:		681 GATEWAY BLVD.
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>tm225889-1_424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: tm225889-1_424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>lg_twistbio-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_twistbio-4clr.jpg

</DOCUMENT>
</SEC-DOCUMENT>