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License, Acquisitions and Other Agreements - Yale University Agreement (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 9 Months Ended
--- | --- | --- | ---
Jan. 31, 2021 | May 31, 2019 | Sep. 30, 2024 | Sep. 30, 2023 | Sep. 30, 2024 | Sep. 30, 2023
License and other agreements |  |  |  |  |  |
Milestone payment to be paid upon regulatory achievement |  |  | $ 641,975,000 |  | $ 641,975,000 |
Research and development |  |  | 157,607,000 | $ 95,517,000 | 628,398,000 | $ 238,468,000
Development milestone payment to be paid |  |  | 140,650,000 |  | 140,650,000 |
Commercial milestone payment to be paid |  |  | 2,150,450,000 |  | 2,150,450,000 |
Yale University | Yale Arrangement |  |  |  |  |  |
License and other agreements |  |  |  |  |  |
Milestone payment to be paid upon regulatory achievement |  |  | 2,000,000 |  | 2,000,000 |
Minimum annual royalty payment to be paid upon sale of product |  | $ 1,000,000 |  |  |  |
Research and development |  |  | 0 | 0 | 0 | 0
Yale University | Yale MoDE Agreement |  |  |  |  |  |
License and other agreements |  |  |  |  |  |
Minimum annual royalty payment to be paid upon sale of product | $ 1,000,000 |  |  |  |  |
Research and development |  |  | 0 | $ 0 | 150,000 | $ 0
Development milestone payment to be paid |  |  | 650,000 |  | 650,000 |
Commercial milestone payment to be paid |  |  | $ 2,950,000 |  | $ 2,950,000 |
Initial term of agreement (in years) | 20 years |  |  |  |  |

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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 55 -Paragraph 48 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482785/280-10-55-48 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 985 -SubTopic 20 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481283/985-20-50-2 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 730 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482916/730-10-50-1 Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 912 -SubTopic 730 -Name Accounting Standards Codification -Section 25 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479532/912-730-25-1 + Details
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