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Shareholders' Equity (Tables) | 9 Months Ended
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Sep. 30, 2024
Stockholders' Equity Note [Abstract] |
Schedule of changes in shareholders' equity (deficit) | Changes in shareholders’ equity for the three and nine months ended September 30, 2024 and September 30, 2023 were as follows:
|  | Common Shares |  |  |  |  |  |  |  |  |  |
|  | Shares |  | Amount |  |  |  | Additional Paid-in Capital |  | Accumulated Deficit |  | Accumulated Other Comprehensive Loss |  | Total Shareholders' Equity
Balances as of December 31, 2023 |  | 81,115,723 |  |  | $ | 887,528 |  |  |  |  | $ | 39,804 |  |  | $ | (499,292) |  |  | $ | (65) |  |  | $ | 427,975 |
Net loss |  | — |  |  | — |  |  |  |  | — |  |  | (179,504) |  |  | — |  |  | (179,504) |
Issuance of common shares as payment for acquisition of IPR&D asset |  | 242,958 |  |  | 10,347 |  |  |  |  | — |  |  | — |  |  | — |  |  | 10,347 |
Issuance of common shares as payment under license and other agreements |  | 97,233 |  |  | 5,637 |  |  |  |  | — |  |  | — |  |  | — |  |  | 5,637 |
Issuance of common shares under 2022 Equity Incentive Plan |  | 351,307 |  |  | 7,452 |  |  |  |  | (5,296) |  |  | — |  |  | — |  |  | 2,156 |
Non-cash share-based compensation expense |  | — |  |  | — |  |  |  |  | 34,877 |  |  | — |  |  | — |  |  | 34,877 |
Other comprehensive loss |  | — |  |  | — |  |  |  |  | — |  |  | — |  |  | (41) |  |  | (41) |
Balances as of March 31, 2024 |  | 81,807,221 |  |  | 910,964 |  |  |  |  | 69,385 |  |  | (678,796) |  |  | (106) |  |  | 301,447 |
Net loss |  | — |  |  | — |  |  |  |  | — |  |  | (319,771) |  |  | — |  |  | (319,771) |
Issuance of common shares, net of offering costs |  | 8,544,951 |  |  | 317,720 |  |  |  |  | — |  |  | — |  |  | — |  |  | 317,720 |
Issuance of common shares as payment for acquisition of IPR&D asset |  | 10,452 |  |  | 446 |  |  |  |  | — |  |  | — |  |  | — |  |  | 446 |
Issuance of common shares as payment under license and other agreements |  | 1,872,874 |  |  | 65,981 |  |  |  |  | — |  |  | — |  |  | — |  |  | 65,981 |
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan |  | 110,834 |  |  | 3,442 |  |  |  |  | (1,125) |  |  | — |  |  | — |  |  | 2,317 |
Issuance of warrant as payment under license agreement |  | — |  |  | — |  |  |  |  | 3,340 |  |  | — |  |  | — |  |  | 3,340 |
Non-cash share-based compensation expense |  | — |  |  | — |  |  |  |  | 12,232 |  |  | — |  |  | — |  |  | 12,232 |
Other comprehensive income |  | — |  |  | — |  |  |  |  | — |  |  | — |  |  | 28 |  |  | 28 |
Balances as of June 30, 2024 |  | 92,346,332 |  |  | 1,298,553 |  |  |  |  | 83,832 |  |  | (998,567) |  |  | (78) |  |  | 383,740 |
Net loss |  | — |  |  | — |  |  |  |  | — |  |  | (160,304) |  |  | — |  |  | (160,304) |
Issuance of common shares, net of offering costs |  | 2,154,857 |  |  | 76,361 |  |  |  |  | — |  |  | — |  |  | — |  |  | 76,361 |
Issuance of common shares as payment for acquisition of IPR&D asset |  | 428 |  |  | 18 |  |  |  |  | — |  |  | — |  |  | — |  |  | 18 |
Issuance of common shares under 2022 Equity Incentive Plan |  | 397,422 |  |  | 6,758 |  |  |  |  | (2,954) |  |  | — |  |  | — |  |  | 3,804 |
Issuance of common shares as payment under license and other agreements |  | 154 |  |  | 9 |  |  |  |  | — |  |  | — |  |  | — |  |  | 9 |
Non-cash share-based compensation expense |  | — |  |  | — |  |  |  |  | 12,160 |  |  | — |  |  | — |  |  | 12,160 |
Other comprehensive income |  | — |  |  | — |  |  |  |  | — |  |  | — |  |  | 218 |  |  | 218 |
Balance as of September 30, 2024 |  | 94,899,193 |  |  | $ | 1,381,699 |  |  |  |  | $ | 93,038 |  |  | $ | (1,158,871) |  |  | $ | 140 |  |  | $ | 316,006 |
|  | Common Shares |  |  |  |  |  |  |  |  |  |
|  | Shares |  | Amount |  |  |  | Additional Paid-in Capital |  | Accumulated Deficit |  | Accumulated Other Comprehensive Income |  | Total Shareholders' Equity
Balances as of December 31, 2022 |  | 68,190,479 |  |  | $ | 615,742 |  |  |  |  | $ | 13,869 |  |  | $ | (91,124) |  |  | $ | 284 |  |  | $ | 538,771 |
Net loss |  | — |  |  | — |  |  |  |  | — |  |  | (70,492) |  |  | — |  |  | (70,492) |
Issuance of common shares under 2022 Equity Incentive Plan |  | 22,000 |  |  | 504 |  |  |  |  | (172) |  |  | — |  |  | — |  |  | 332 |
Non-cash share-based compensation expense |  | — |  |  | — |  |  |  |  | 3,765 |  |  | — |  |  | — |  |  | 3,765 |
Other comprehensive loss |  | — |  |  | — |  |  |  |  | — |  |  | — |  |  | (118) |  |  | (118) |
Balances as of March 31, 2023 |  | 68,212,479 |  |  | 616,246 |  |  |  |  | 17,462 |  |  | (161,616) |  |  | 166 |  |  | 472,258 |
Net loss |  | — |  |  | — |  |  |  |  | — |  |  | (90,346) |  |  | — |  |  | (90,346) |
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan |  | 104,474 |  |  | 1,264 |  |  |  |  | (470) |  |  | — |  |  | — |  |  | 794 |
Non-cash share-based compensation expense |  | — |  |  | — |  |  |  |  | 4,695 |  |  | — |  |  | — |  |  | 4,695 |
Other comprehensive loss |  | — |  |  | — |  |  |  |  | — |  |  | — |  |  | (146) |  |  | (146) |
Balance as of June 30, 2023 |  | 68,316,953 |  |  | 617,510 |  |  |  |  | 21,687 |  |  | (251,962) |  |  | 20 |  |  | 387,255 |
Net loss |  | — |  |  | — |  |  |  |  | — |  |  | (102,574) |  |  | — |  |  | (102,574) |
Issuance of common shares under 2022 Equity Incentive Plan |  | 47,190 |  |  | 1,251 |  |  |  |  | (520) |  |  | — |  |  | — |  |  | 731 |
Non-cash share-based compensation expense |  | — |  |  | — |  |  |  |  | 4,456 |  |  | — |  |  | — |  |  | 4,456 |
Other comprehensive income |  | — |  |  | — |  |  |  |  | — |  |  | — |  |  | 138 |  |  | 138 |
Balance as of September 30, 2023 |  | 68,364,143 |  |  | $ | 618,761 |  |  |  |  | $ | 25,623 |  |  | $ | (354,536) |  |  | $ | 158 |  |  | $ | 290,006 |

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- Definition Tabular disclosure of changes in the separate accounts comprising stockholders' equity (in addition to retained earnings) and of the changes in the number of shares of equity securities during at least the most recent annual fiscal period and any subsequent interim period presented is required to make the financial statements sufficiently informative if both financial position and results of operations are presented. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -SubTopic 10 -Topic 505 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-2 + Details
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