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Shareholders' Equity - Changes in Shareholders' Deficit (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Dec. 31, 2023
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Increase (Decrease) in Stockholders' Equity [Roll Forward]                    
Net loss $ (160,304)       $ (102,574)     $ (659,579) $ (263,412)  
Other comprehensive (loss) income 218       138     205 (126)  
Total Shareholders' Equity                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                    
Beginning balance 383,740 $ 301,447 $ 427,975 $ 290,006 387,255 $ 472,258 $ 538,771 427,975 538,771 $ 290,006
Net loss (160,304) (319,771) (179,504)   (102,574) (90,346) (70,492)      
Issuance of common shares, net of offering costs 76,361 317,720                
Issuance of common shares as payment for assets 18 446 10,347              
Issuance of common shares as payment under license and other agreements 9 65,981 5,637              
Issuance of common shares under 2022 Equity Incentive Plan 3,804   2,156   731   332      
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan   2,317       794        
Issuance of warrant as payment under license agreement   3,340                
Non-cash share-based compensation expense 12,160 12,232 34,877   4,456 4,695 3,765      
Other comprehensive (loss) income 218 28 (41)   138 (146) (118)      
Ending balance $ 316,006 $ 383,740 $ 301,447 $ 427,975 $ 290,006 $ 387,255 $ 472,258 $ 316,006 $ 290,006 $ 316,006
Common Shares                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                    
Beginning balance (in shares) 92,346,332 81,807,221 81,115,723 68,364,143 68,316,953 68,212,479 68,190,479 81,115,723 68,190,479 68,364,143
Beginning balance $ 1,298,553 $ 910,964 $ 887,528 $ 618,761 $ 617,510 $ 616,246 $ 615,742 $ 887,528 $ 615,742 $ 618,761
Issuance of common shares, net of offering costs (in shares) 2,154,857 8,544,951                
Issuance of common shares, net of offering costs $ 76,361 $ 317,720                
Issuance of common shares as payment for assets (in shares) 428 10,452 242,958              
Issuance of common shares as payment for assets $ 18 $ 446 $ 10,347              
Issuance of common shares as payment under license and other agreements (in shares) 154 1,872,874 97,233              
Issuance of common shares as payment under license and other agreements $ 9 $ 65,981 $ 5,637              
Issuance of common shares under equity incentive plan (shares) 397,422   351,307   47,190   22,000      
Issuance of common shares under 2022 Equity Incentive Plan $ 6,758   $ 7,452   $ 1,251   $ 504      
Issuance of common shares under equity incentive plan and employee share purchase plan (in shares)   110,834       104,474        
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan   $ 3,442       $ 1,264        
Ending balance (in shares) 94,899,193 92,346,332 81,807,221 81,115,723 68,364,143 68,316,953 68,212,479 94,899,193 68,364,143 94,899,193
Ending balance $ 1,381,699 $ 1,298,553 $ 910,964 $ 887,528 $ 618,761 $ 617,510 $ 616,246 $ 1,381,699 $ 618,761 $ 1,381,699
Additional Paid-in Capital                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                    
Beginning balance 83,832 69,385 39,804 25,623 21,687 17,462 13,869 39,804 13,869 25,623
Issuance of common shares under 2022 Equity Incentive Plan (2,954)   (5,296)   (520)   (172)      
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan   (1,125)       (470)        
Issuance of warrant as payment under license agreement   3,340                
Non-cash share-based compensation expense 12,160 12,232 34,877   4,456 4,695 3,765      
Ending balance 93,038 83,832 69,385 39,804 25,623 21,687 17,462 93,038 25,623 93,038
Accumulated Deficit                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                    
Beginning balance (998,567) (678,796) (499,292) (354,536) (251,962) (161,616) (91,124) (499,292) (91,124) (354,536)
Net loss (160,304) (319,771) (179,504)   (102,574) (90,346) (70,492)      
Ending balance (1,158,871) (998,567) (678,796) (499,292) (354,536) (251,962) (161,616) (1,158,871) (354,536) (1,158,871)
Accumulated Other Comprehensive Loss                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                    
Beginning balance (78) (106) (65) 158 20 166 284 (65) 284 158
Other comprehensive (loss) income 218 28 (41)   138 (146) (118)      
Ending balance $ 140 $ (78) $ (106) $ (65) $ 158 $ 20 $ 166 $ 140 $ 158 $ 140