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v3.26.1

License, Acquisitions and Other Agreements - Acquisitions (Details) - USD ($) |  |  | 1 Months Ended | 3 Months Ended | 6 Months Ended |  |
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May 01, 2025 | May 01, 2024 | Jun. 30, 2025 | May 31, 2024 | Jan. 31, 2024 | Jun. 30, 2026 | Jun. 30, 2025 | Jun. 30, 2026 | Jun. 30, 2025 | Dec. 31, 2025 | May 03, 2024
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Success-based milestone payments, based on regulatory approval |  |  |  |  |  | $ 185,000,000 |  | $ 185,000,000 |  |  |
Additional regulatory milestone payments |  |  |  |  |  | 60,000,000 |  | 60,000,000 |  |  |
Pyramid |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Upfront payment of common shares, shares (in shares) |  |  |  |  | 255,794,000 |  |  |  |  |  |
Upfront payment of common shares, value |  |  |  |  | $ 10,894,000 |  |  |  |  |  |
Research and development |  |  |  |  |  | 0 | $ 0 | 0 | $ 0 |  |
Pyramid | Developmental And Regulatory Milestones, First Asset | Lead Asset |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Success-based payments |  |  |  |  |  | 5,000,000 |  | 5,000,000 |  |  |
Pyramid | Developmental And Regulatory Milestones, Second Asset | Second Asset |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Success-based payments |  |  |  |  |  | 30,000,000 |  | 30,000,000 |  |  |
Pyramid | Commercial Sales-Based Milestones |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Success-based payments |  |  |  |  |  | $ 40,000,000 |  | $ 40,000,000 |  |  |
Purchase Agreement, Knopp Amendment |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Number of securities called by warrants (in shares) |  | 294,195 |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) |  | $ 67.98 |  |  |  |  |  |  |  |  |
Warrants, fair value disclosure |  | $ 3,340,000 |  |  |  |  |  |  |  |  |
Forward Contract Liability, 2025 Addtional Consideration |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Common shares issuable, value (in shares) | 3,588,688 |  |  |  |  |  |  |  |  |  |
Forward Contract Liability, 2025 Addtional Consideration | Level 3 |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Gain (loss) on change in fair value of forward contract and derivative liability |  |  |  |  |  |  | 21,894,000 |  | 20,074,000 |  |
Fair value |  | 63,940,000 |  |  |  |  |  |  |  | $ 42,710,000 |
Forward contract, current |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Forward contract and derivative liability |  |  |  |  |  |  |  |  |  |  | $ 75,220,000
Derivative Liability, 2024 Additional Consideration | Level 3 |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Gain (loss) on change in fair value of forward contract and derivative liability |  |  |  | $ 9,239,000 |  |  |  |  |  |  |
2024 Additional Consideration True-up | Level 3 |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Fair value |  |  |  |  |  |  |  |  |  |  | 15,540,000
2025 Additional Consideration True-up | Level 3 |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Gain (loss) on change in fair value of forward contract and derivative liability |  |  |  |  |  |  | $ (10,970,000) |  | $ (12,760,000) |  |
Fair value |  |  |  |  |  |  |  |  |  |  | $ 13,810,000
Purchase Agreement, Knopp Amendment |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Issuance of common shares, net of offering costs |  | $ 75,000,000 |  |  |  |  |  |  |  |  |
Fair value first anniversary of execution period |  | 60 days |  |  |  |  |  |  |  |  |
Purchase Agreement, Knopp Amendment, 2025 Additional Consideration |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Fair value first anniversary of execution period |  | 60 days |  |  |  |  |  |  |  |  |
Common shares issuable, value |  | $ 75,000,000 |  |  |  |  |  |  |  |  |
Purchase Agreement, Knopp Amendment |  |  |  |  |  |  |  |  |  |  |
License and other agreements |  |  |  |  |  |  |  |  |  |  |
Common stock issued (in shares) |  |  | 3,588,688 | 1,872,874 |  |  |  |  |  |  |
Issuance of common shares, net of offering costs |  |  | $ 51,426,000 | $ 65,981,000 |  |  |  |  |  |  |

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