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Share-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2017

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Share Option Activity

Share Options

Share option activity under the 2014 Plan for the nine months ended September 30, 2017 is summarized as follows:

		Number of Shares				Weighted- Average Exercise Price
Options outstanding as of January 1, 2017			3,577,766			$	10.58
Granted			414,000				25.55
Exercised			(76,319	)			4.24
Canceled or forfeited			(109,652	)			16.79
Outstanding as of September 30, 2017			3,805,795				12.26
Options exercisable as of September 30, 2017			2,042,259				6.62
Options unvested as of September 30, 2017			1,763,536				18.79

Summary of Restricted Share Units ("RSU") Activity

Restricted Share Units

Restricted share unit (“RSU”) activity for the nine months ended September 30, 2017 is summarized as follows:

		RSUs				Average Grant Date Fair Value (in dollars per share)
RSUs Outstanding as of January 1, 2017			22,750			$	21.69
Granted			170,859				29.05
Vested			(22,750	)			21.69
Canceled or forfeited			(8,579	)			29.05
RSUs Outstanding at September 30, 2017			162,280				29.05

Summary of Share-based Compensation Expense Classified in Consolidated Statements of Operations

Share-based compensation expense for the three and nine months ended September 30, 2017 and 2016 was classified in the consolidated statements of operations as follows:

		Three Months Ended September 30,								Nine Months Ended September 30,
		2017				2016				2017				2016
		(in thousands)
Research and development expenses		$	1,759			$	1,695			$	5,527			$	3,207
General and administrative expenses			1,241				486				3,439				1,112
Total share-based compensation		$	3,000			$	2,181			$	8,966			$	4,319

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Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901

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