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Unaudited Consolidated Statements of Operations - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Income Statement [Abstract]        
Revenue $ 676 $ 392 $ 2,028 $ 809
Operating expenses:        
Research and development 20,097 13,686 53,940 26,823
General and administrative 7,571 3,939 20,088 10,809
Total operating expenses 27,668 17,625 74,028 37,632
Loss from operations (26,992) (17,233) (72,000) (36,823)
Other income (expense):        
Dividend income 515   1,287  
Interest income (expense), net 1 118 5 328
Other income (expense), net (75) (36) (211) (25)
Total other income (expense), net 441 82 1,081 303
Loss before income taxes (26,551) (17,151) (70,919) (36,520)
Income tax benefit (provision) 416 (384) (905) (427)
Net loss $ (26,135) $ (17,535) $ (71,824) $ (36,947)
Net loss per share attributable to ordinary shareholders— basic and diluted $ (0.94) $ (0.75) $ (2.75) $ (1.64)
Weighted-average ordinary shares used in computing net loss per share attributable to ordinary shareholders—basic and diluted 27,758,792 23,445,673 26,078,696 22,571,575