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Net Loss Per Ordinary Share (Tables)

12 Months Ended

Dec. 31, 2018

Earnings Per Share [Abstract]

Summary of Basic and Diluted Net Loss Per Ordinary Share Outstanding

Basic loss per share is computed by dividing net loss attributable to ordinary shareholders by the weighted-average number of ordinary shares outstanding:

		Year Ended December 31,
		2018				2017				2016
		(in thousands except share and per share data)
Numerator:
Net loss attributable to ordinary shareholders		$	(146,653	)		$	(101,980	)		$	(55,660	)
Denominator:
Weighted-average ordinary shares outstanding			28,970,404				26,513,382				22,800,628
Net loss per share, basic and diluted		$	(5.06	)		$	(3.85	)		$	(2.44	)

Anti-Dilutive Shares Excluded from Calculation of Diluted Net Loss Per Ordinary Share

The following potential ordinary shares, presented based on amounts outstanding at each period end, were excluded from the calculation of diluted net loss per share attributable to ordinary shareholders for the periods indicated because including them would have had an anti-dilutive effect:

		As of December 31,
		2018				2017
Options to purchase ordinary shares			4,016,590				3,767,130
RSUs			408,521				154,459
Series A preferred shares			3,901,348				3,901,348

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- References

No definition available.

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- Definition

Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257

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- Definition

Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257

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