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Related Parties - Additional Information (Detail) - USD ($) $ in Thousands	9 Months Ended	12 Months Ended
	Sep. 30, 2018	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Third-Party Investor [Member]
Related Party Transaction [Line Items]
Related party transaction amount			$ 100
Shin Nippon Biomedical Laboratories Ltd. (SNBL) [Member]
Related Party Transaction [Line Items]
Payment for contract research services	$ 1,300		$ 500	$ 400
Scientific Advisor [Member] | Consulting Agreement [Member]
Related Party Transaction [Line Items]
Consulting agreement termination notice period		14 days
Consulting service expenses		$ 13

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+ References

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- Definition

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