<SEC-DOCUMENT>0001752724-21-039950.txt : 20210225
<SEC-HEADER>0001752724-21-039950.hdr.sgml : 20210225
<ACCEPTANCE-DATETIME>20210225113805
ACCESSION NUMBER:		0001752724-21-039950
CONFORMED SUBMISSION TYPE:	NPORT-P
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20201231
FILED AS OF DATE:		20210225
PERIOD START:           	20201231

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BlackRock Science & Technology Trust II
		CENTRAL INDEX KEY:			0001768666
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		NPORT-P
		SEC ACT:		1940 Act
		SEC FILE NUMBER:	811-23428
		FILM NUMBER:		21678012

	BUSINESS ADDRESS:	
		STREET 1:		100 BELLEVUE PARKWAY
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19809
		BUSINESS PHONE:		800 882 0052

	MAIL ADDRESS:	
		STREET 1:		100 BELLEVUE PARKWAY
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19809

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BlackRock Science & technology Trust II
		DATE OF NAME CHANGE:	20190221
</SEC-HEADER>
<DOCUMENT>
<TYPE>NPORT-P
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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        <name>Unqork Inc. SERIES C</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Online Ventures Pty Limited</name>
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        <fairValLevel>3</fairValLevel>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>CREDIT SUISSE INTERNATIONAL</name>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>StoneCo Ltd</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>TESLA INC FEB21 720 CALL</title>
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        <name>Options Clearing Corp.</name>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
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        <name>Zscaler Inc</name>
        <lei>529900MZ0RTK1BWRNF46</lei>
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        <fairValLevel>1</fairValLevel>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>NCSoft Corp</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Inphi Corp</name>
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        <name>MORGAN STANLEY &amp; CO. INTERNATIONAL</name>
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        <name>GOLDMAN SACHS INTERNATIONAL</name>
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        <name>Options Clearing Corp.</name>
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        <name>Xero Ltd</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <lei>G5GSEF7VJP5I7OUK5573</lei>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <valUSD>-241425.00000000</valUSD>
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        <isRestrictedSec>N</isRestrictedSec>

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        <name>MORGAN STANLEY &amp; CO. INTERNATIONAL</name>
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        <name>Dragoneer Growth Opportunities Corp</name>
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        <name>MORGAN STANLEY &amp; CO. INTERNATIONAL</name>
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        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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        <isRestrictedSec>N</isRestrictedSec>

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        <name>GOLDMAN SACHS INTERNATIONAL</name>
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        <lei>N/A</lei>
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        <name>BARCLAYS BANK PLC</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
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        <name>MORGAN STANLEY &amp; CO. INTERNATIONAL</name>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>GOLDMAN SACHS INTERNATIONAL</name>
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      <invstOrSec>
        <name>Square Inc</name>
        <lei>549300OHIIUWSTIZME52</lei>
        <title>Square Inc</title>
        <cusip>852234103</cusip>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Delivery Hero SE</name>
        <lei>529900C3EX1FZGE48X78</lei>
        <title>Delivery Hero SE</title>
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        <name>FISKER PIPE</name>
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        <name>Cazoo Ltd, SERIES A</name>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>MERCADOLIBRE INC JAN21 1600 CALL</title>
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        <name>GOLDMAN SACHS INTERNATIONAL</name>
        <lei>W22LROWP2IHZNBB6K528</lei>
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        <name>GOLDMAN SACHS INTERNATIONAL</name>
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        <name>STMicroelectronics NV</name>
        <lei>213800Z8NOHIKRI42W10</lei>
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        <name>Options Clearing Corp.</name>
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        <name>SOCIETE GENERALE</name>
        <lei>O2RNE8IBXP4R0TD8PU41</lei>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Adyen NV</name>
        <lei>724500973ODKK3IFQ447</lei>
        <title>Adyen NV</title>
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        <lei>N/A</lei>
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        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <isRestrictedSec>N</isRestrictedSec>

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      <invstOrSec>
        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <balance>-86.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-154155.00000000</valUSD>
        <pctVal>-0.00509814913</pctVal>
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        <assetCat>DE</assetCat>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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            <exercisePrice>240.00000000</exercisePrice>
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            <expDt>2021-01-15</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>-58055.47000000</unrealizedAppr>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>SNAP INC JAN21 53.5 CALL</title>
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          <other otherDesc="BlackRock Identifier" value="Z954RUXT6"/>
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        <balance>-765.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-102510.00000000</valUSD>
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        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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              <counterpartyName>Options Clearing Corp.</counterpartyName>
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            <delta>XXXX</delta>
            <unrealizedAppr>148908.48000000</unrealizedAppr>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>CROWDSTRIKE HOLDINGS INC JAN21 200 CALL</title>
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        <valUSD>-175175.00000000</valUSD>
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        <assetCat>DE</assetCat>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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              <counterpartyName>Options Clearing Corp.</counterpartyName>
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            <delta>XXXX</delta>
            <unrealizedAppr>-121571.74000000</unrealizedAppr>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>LATTICE SEMICONDUCTOR CORP FEB21 45 CALL</title>
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          <other otherDesc="BlackRock Identifier" value="Z955D0581"/>
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        <valUSD>-301725.00000000</valUSD>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>SHOPIFY INC JAN21 1070 CALL</title>
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        <name>Options Clearing Corp.</name>
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        <name>Kakao Corp</name>
        <lei>988400FTKUBQXKVZP434</lei>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <isRestrictedSec>N</isRestrictedSec>

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              <counterpartyName>Options Clearing Corp.</counterpartyName>
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        <name>Options Clearing Corp.</name>
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        <name>JP MORGAN CHASE BANK</name>
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        <name>Options Clearing Corp.</name>
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        <name>Databricks, Inc.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>BE Semiconductor Industries NV</name>
        <lei>7245007A1YFLI2GNYX06</lei>
        <title>BE Semiconductor Industries NV</title>
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        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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        <name>CITIBANK NA</name>
        <lei>E57ODZWZ7FF32TWEFA76</lei>
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        <name>MORGAN STANLEY &amp; CO. INTERNATIONAL</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>DataRobot, Inc., SERIES F</name>
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        <fairValLevel>3</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>CREE INC JAN21 77.5 CALL</title>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>ZOOMINFO TECHNOLOGIES INC JAN21 50 CALL</title>
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        <name>SUSQUEHANNA FINANCIAL GROUP LLLP</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>SHIFT4 PAYMENTS INC FEB21 75 CALL</title>
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        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Magazine Luiza SA</name>
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        <name>JEFFERIES LLC</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>UBS AG</name>
        <lei>BFM8T61CT2L1QCEMIK50</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>JP MORGAN CHASE BANK</name>
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        <name>Silergy Corp</name>
        <lei>N/A</lei>
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        <name>Unqork Inc.  Series B</name>
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        <title>Unqork Inc.  Series B</title>
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        <fairValLevel>3</fairValLevel>
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        <name>Cazoo Ltd, SERIES D</name>
        <lei>N/A</lei>
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        <fairValLevel>3</fairValLevel>
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        <name>Locaweb Servicos de Internet SA</name>
        <lei>N/A</lei>
        <title>Locaweb Servicos de Internet SA</title>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>SOCIETE GENERALE</name>
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        <name>ResearchGate GmbH, SERIES D</name>
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        <name>GOLDMAN SACHS INTERNATIONAL</name>
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        <name>Endava PLC</name>
        <lei>213800JJ6CRPCWCQVZ25</lei>
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        <name>Lasertec Corp</name>
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        <title>Lasertec Corp</title>
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        <name>Snorkel AI Inc SERIES B</name>
        <lei>N/A</lei>
        <title>Snorkel AI Inc SERIES B</title>
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        <fairValLevel>2</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>Options Clearing Corp.</name>
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        <name>Tyro Payments Ltd</name>
        <lei>N/A</lei>
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        <fairValLevel>2</fairValLevel>
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        <name>Kingsoft Cloud Holdings Ltd</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>UBS AG</name>
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        <name>The Montreal Exchange / Bourse De Montreal</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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      <invstOrSec>
        <name>Marvell Technology Group Ltd</name>
        <lei>8DF36O58U3QIHUCGZB18</lei>
        <title>Marvell Technology Group Ltd</title>
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        <isRestrictedSec>N</isRestrictedSec>

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        <name>Options Clearing Corp.</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <isRestrictedSec>N</isRestrictedSec>

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        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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        <name>Shopify Inc</name>
        <lei>549300HGQ43STJLLP808</lei>
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        <fairValLevel>1</fairValLevel>
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        <lei>549300AKX7O8JG0O3G77</lei>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>TESLA INC JAN21 640 CALL</title>
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        <name>Twilio Inc</name>
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        <name>Options Clearing Corp.</name>
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        <name>Synopsys Inc</name>
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        <name>Options Clearing Corp.</name>
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        <name>JP MORGAN CHASE BANK</name>
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        <name>Options Clearing Corp.</name>
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        <name>Roku Inc</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>BANK OF AMERICA NA</name>
        <lei>B4TYDEB6GKMZO031MB27</lei>
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        <name>MercadoLibre Inc</name>
        <lei>549300DKPDN9M5S8GB14</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>JP MORGAN CHASE BANK</name>
        <lei>7H6GLXDRUGQFU57RNE97</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>The Montreal Exchange / Bourse De Montreal</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <fairValLevel>3</fairValLevel>
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        <name>BARCLAYS BANK PLC</name>
        <lei>G5GSEF7VJP5I7OUK5573</lei>
        <title>BRWAMPBS0 JAN21 DHER GY CALL JAN21 115.72 CALL</title>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>STONECO LTD JAN21 74 CALL</title>
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      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>LYFT INC JAN21 57.5 CALL</title>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
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        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>ROKU INC JAN21 335 CALL</title>
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        <name>Options Clearing Corp.</name>
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      <invstOrSec>
        <name>SambaNova Systems, Inc. SERIES C</name>
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        <curCd>USD</curCd>
        <valUSD>38029696.00000000</valUSD>
        <pctVal>1.257702065616</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>LATTICE SEMICONDUCTOR CORP JAN21 45 CALL</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="Z94URT8U7"/>
        </identifiers>
        <balance>-729.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-158557.50000000</valUSD>
        <pctVal>-0.00524374676</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="derivative" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Options Clearing Corp.</counterpartyName>
              <counterpartyLei>549300CII6SLYGKNHA04</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>Lattice Semiconductor Corp</issuerName>
                <issueTitle>Lattice Semiconductor Corp</issueTitle>
                <identifiers>
                  <cusip value="518415104"/>
                  <isin value="US5184151042"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100.00000000</shareNo>
            <exercisePrice>45.00000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2021-01-15</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>-27704.26000000</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Dragoneer Growth Opportunities Corp</name>
        <lei>N/A</lei>
        <title>Dragoneer Growth Opportunities Corp</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="KYG283021007"/>
        </identifiers>
        <balance>733300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9730891.00000000</valUSD>
        <pctVal>0.321815922772</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>SNAP INC JAN21 60 CALL</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="Z954U0X68"/>
        </identifiers>
        <balance>-527.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-21870.50000000</valUSD>
        <pctVal>-0.00072329195</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="derivative" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Options Clearing Corp.</counterpartyName>
              <counterpartyLei>549300CII6SLYGKNHA04</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>Snap Inc</issuerName>
                <issueTitle>Snap Inc</issueTitle>
                <identifiers>
                  <cusip value="83304A106"/>
                  <isin value="US83304A1060"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100.00000000</shareNo>
            <exercisePrice>60.00000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2021-01-22</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>40189.89000000</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BARCLAYS BANK PLC</name>
        <lei>G5GSEF7VJP5I7OUK5573</lei>
        <title>BRWAJXPD5 JAN21 SOI FP CALL JAN21 141.44 CALL</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="BRWAJXPD5"/>
        </identifiers>
        <balance>-14600.00000000</balance>
        <units>NC</units>
        <currencyConditional curCd="EUR" exchangeRt="0.81856500"/>
        <valUSD>-308783.95000000</valUSD>
        <pctVal>-0.01021197255</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="derivative" issuerCat="OTHER"/>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>BARCLAYS BANK PLC</counterpartyName>
              <counterpartyLei>G5GSEF7VJP5I7OUK5573</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>SOITEC</issuerName>
                <issueTitle>SOITEC</issueTitle>
                <identifiers>
                  <isin value="FR0013227113"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>1.00000000</shareNo>
            <exercisePrice>141.44000000</exercisePrice>
            <exercisePriceCurCd>EUR</exercisePriceCurCd>
            <expDt>2021-01-12</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>-207115.69000000</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Atlassian Corp PLC</name>
        <lei>549300AGBII4MWBVJY22</lei>
        <title>Atlassian Corp PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="GB00BZ09BD16"/>
        </identifiers>
        <balance>101575.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23755345.25000000</valUSD>
        <pctVal>0.785626758372</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Options Clearing Corp.</name>
        <lei>549300CII6SLYGKNHA04</lei>
        <title>SHOPIFY INC JAN21 1180 CALL</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="Z95541ZG8"/>
        </identifiers>
        <balance>-30.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-125250.00000000</valUSD>
        <pctVal>-0.00414221517</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="derivative" issuerCat="OTHER"/>
        <invCountry>CA</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Options Clearing Corp.</counterpartyName>
              <counterpartyLei>549300CII6SLYGKNHA04</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>Shopify Inc</issuerName>
                <issueTitle>Shopify Inc</issueTitle>
                <identifiers>
                  <isin value="CA82509L1076"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100.00000000</shareNo>
            <exercisePrice>1180.00000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2021-01-29</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>100462.01000000</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GOLDMAN SACHS INTERNATIONAL</name>
        <lei>W22LROWP2IHZNBB6K528</lei>
        <title>BRWAJXPF0 JAN21 DHER GY CALL JAN21 117.9675 CALL</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="BRWAJXPF0"/>
        </identifiers>
        <balance>-58700.00000000</balance>
        <units>NC</units>
        <currencyConditional curCd="EUR" exchangeRt="0.81856500"/>
        <valUSD>-890432.89000000</valUSD>
        <pctVal>-0.02944802096</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="derivative" issuerCat="OTHER"/>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>GOLDMAN SACHS INTERNATIONAL</counterpartyName>
              <counterpartyLei>W22LROWP2IHZNBB6K528</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>Delivery Hero SE</issuerName>
                <issueTitle>Delivery Hero SE</issueTitle>
                <identifiers>
                  <isin value="DE000A2E4K43"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>1.00000000</shareNo>
            <exercisePrice>117.96750000</exercisePrice>
            <exercisePriceCurCd>EUR</exercisePriceCurCd>
            <expDt>2021-01-12</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>-419564.26000000</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GrubMarket, Inc. SERIES D</name>
        <lei>N/A</lei>
        <title>GrubMarket, Inc. SERIES D</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="BRW6USSS6"/>
        </identifiers>
        <balance>1762969.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8391732.44000000</valUSD>
        <pctVal>0.277527835717</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Snyk Ltd</name>
        <lei>N/A</lei>
        <title>Snyk Ltd</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="BlackRock Identifier" value="BRWA1EW63"/>
        </identifiers>
        <balance>360378.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1787402.80000000</valUSD>
        <pctVal>0.059112231495</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2021-01-28</ncom:dateSigned>
      <ncom:nameOfApplicant>BlackRock Science and Technology Trust II</ncom:nameOfApplicant>
      <ncom:signature>Ann Frechette</ncom:signature>
      <ncom:signerName>Ann Frechette</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
