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Related-party Transactions (Details Textual) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Related Party Transaction [Line Items]    
Accounts Payable, Related Parties, Current $ 0 $ 576,000
Related Party Transaction, Purchases from Related Party 522,000 $ 576,000
Related Party Transaction, Amounts of Transaction 0  
Research and Development Expense [Member]    
Related Party Transaction [Line Items]    
Related Party Transaction, Amounts of Transaction $ 2,200,000