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v3.21.1

CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS’ EQUITY - USD ($) shares in Thousands, $ in Thousands | Total | Cumulative Effect, Period of Adoption, Adjustment | Ordinary shares | Preferred shares | Additional paid-in capital | Additional paid-in capital Cumulative Effect, Period of Adoption, Adjustment | Accumulated deficit | Accumulated deficit Cumulative Effect, Period of Adoption, Adjustment | Accumulated other comprehensive (loss) income | Treasury shares
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2019 |  |  | 42,927 | 0 |  |  |  |  |  | 5,407
Beginning balance at Dec. 31, 2019 | $ (29,199) |  | $ 429 | $ 0 | $ 434,391 |  | $ (391,215) |  | $ (22,806) | $ (49,998)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |
Net loss | (865) |  |  |  |  |  | (865) |  |  |
Other comprehensive income (loss) | (821) |  |  |  |  |  |  |  | (821) |
Exercise of stock options (in shares) |  |  | 146 |  |  |  |  |  |  |
Exercise of stock options | 1,389 |  | $ 2 |  | 1,387 |  |  |  |  |
Vesting of restricted shares (in shares) |  |  | 19 |  |  |  |  |  |  |
Vesting of restricted shares | 0 |  |  |  |  |  |  |  |  |
Employee share purchase plan share issuance (in shares) |  |  | 40 |  |  |  |  |  |  |
Employee share purchase plan share issuance | 88 |  |  |  | 88 |  |  |  |  |
Stock-based compensation expense | 742 |  |  |  | 742 |  |  |  |  |
February 2020 private placement (in shares) |  |  | 8,680 | 488 |  |  |  |  |  |
February 2020 private placement | 60,733 |  | $ 87 | $ 5 | 60,641 |  |  |  |  |
Ending balance (in shares) at Mar. 31, 2020 |  |  | 51,812 | 488 |  |  |  |  |  | 5,407
Ending balance at Mar. 31, 2020 | 32,067 |  | $ 518 | $ 5 | 497,249 |  | (392,080) |  | (23,627) | $ (49,998)
Beginning balance (in shares) at Dec. 31, 2019 |  |  | 42,927 | 0 |  |  |  |  |  | 5,407
Beginning balance at Dec. 31, 2019 | $ (29,199) |  | $ 429 | $ 0 | 434,391 |  | (391,215) |  | (22,806) | $ (49,998)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |
Accounting Standards Update [Extensible List] | avdl:AccountingStandardsUpdate202006Member |  |  |  |  |  |  |  |  |
Ending balance (in shares) at Dec. 31, 2020 |  |  | 58,396 | 488 |  |  |  |  |  |
Ending balance at Dec. 31, 2020 | $ 162,266 | $ (12,939) | $ 583 | $ 5 | 566,916 | $ (26,699) | (384,187) | $ 13,760 | (21,051) |
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |  |  |  |
Net loss | (13,445) |  |  |  |  |  | (13,445) |  |  |
Other comprehensive income (loss) | (1,255) |  |  |  |  |  |  |  | (1,255) |
Exercise of stock options (in shares) |  |  | 23 |  |  |  |  |  |  |
Exercise of stock options | 106 |  |  |  | 106 |  |  |  |  |
Vesting of restricted shares (in shares) |  |  | 61 |  |  |  |  |  |  |
Vesting of restricted shares | 0 |  | $ 1 |  | (1) |  |  |  |  |
Employee share purchase plan share issuance (in shares) |  |  | 8 |  |  |  |  |  |  |
Employee share purchase plan share issuance | 43 |  |  |  | 43 |  |  |  |  |
Stock-based compensation expense | 1,728 |  |  |  | 1,728 |  |  |  |  |
Ending balance (in shares) at Mar. 31, 2021 |  |  | 58,488 | 488 |  |  |  |  |  |
Ending balance at Mar. 31, 2021 | $ 136,504 |  | $ 584 | $ 5 | $ 542,093 |  | $ (383,872) |  | $ (22,306) |

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