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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2021 | Mar. 31, 2020 | Dec. 31, 2020
Cash flows from operating activities: |  |  |
Net loss | $ (13,445) | $ (865) |
Adjustments to reconcile net loss to net cash provided by operating activities: |  |  |
Depreciation and amortization | 218 | 456 |
Remeasurement of acquisition-related contingent consideration | 0 | 2,478 |
Remeasurement of financing-related contingent consideration | 0 | 310 |
Amortization of debt discount and debt issuance costs | 312 | 1,573 |
Change in deferred tax and income tax deferred charge | (2,534) | (8,440) |
Stock-based compensation expense | 1,728 | 742 |
Gain from the release of certain liabilities | (78) | 0 |
Other adjustments | 561 | 573 |
Net changes in assets and liabilities |  |  |
Accounts receivable | 0 | (517) |
Inventories | 0 | 47 |
Prepaid expenses and other current assets | (3,736) | 899 |
Research and development tax credit receivable | 80 | 160 |
Accounts payable & other current liabilities | (3,789) | (1,187) |
Accrued expenses | (2,112) | (4,905) |
Accrued income taxes | 0 | 2,253 |
Earn-out payments for contingent consideration in excess of acquisition-date fair value | 0 | (1,774) |
Royalty payments for contingent consideration payable in excess of original fair value | 0 | (291) |
Other assets and liabilities | (618) | (3,148) |
Net cash used in operating activities | (23,413) | (11,636) |
Cash flows from investing activities: |  |  |
Purchases of property and equipment | (26) | 0 |
Proceeds from the disposition of the hospital products | 8,250 | 0 |
Proceeds from sales of marketable securities | 40,736 | 14,788 |
Purchases of marketable securities | (37,769) | (1,562) |
Net cash provided by investing activities | 11,191 | 13,226 |
Cash flows from financing activities: |  |  |
Proceeds from the February 2020 private placement | 0 | 60,733 |
Proceeds from stock option exercises and employee stock purchase plan | 149 | 1,477 |
Net cash provided by financing activities | 149 | 62,210 |
Effect of foreign currency exchange rate changes on cash and cash equivalents | (477) | (68) |
Net change in cash and cash equivalents | (12,550) | 63,732 |
Cash and cash equivalents at January 1, | 71,722 | 9,774 | $ 9,774
Cash and cash equivalents at March 31, | 59,172 | 73,506 | $ 71,722
Supplemental disclosures of cash flow information: |  |  |
Interest paid | 3,234 | 3,234 |
Income taxes paid | $ 0 | $ 0 |

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