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Long-Term Debt - Narrative (Details) |  | 3 Months Ended | 6 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Feb. 16, 2018 USD ($) day $ / shares Rate | Jun. 30, 2021 USD ($) | Jun. 30, 2020 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2020 USD ($) | Mar. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Mar. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Interest expense, debt |  | $ 1,930,000 | $ 3,237,000 | $ 3,859,000 | $ 6,427,000 |  |  |  |
Coupon interest expense |  | 1,617,000 | 1,617,000 | 3,234,000 | 3,234,000 |  |  |  |
Amortization of debt discount and debt issuance costs |  | 313,000 | 1,620,000 | 625,000 | 3,193,000 |  |  |  |
Stockholders' equity |  | 118,880,000 | 182,125,000 | 118,880,000 | 182,125,000 | $ 136,504,000 | $ 162,266,000 | $ 32,067,000 | $ (29,199,000)
ADSs, conversion ratio | Rate | 9269.56% |  |  |  |  |  |  |  |
Additional paid-in capital |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Stockholders' equity |  | 544,094,000 | 615,207,000 | 544,094,000 | 615,207,000 | 542,093,000 | 566,916,000 | 497,249,000 | 434,391,000
Accumulated deficit |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Stockholders' equity |  | (403,453,000) | $ (361,206,000) | (403,453,000) | $ (361,206,000) | $ (383,872,000) | (384,187,000) | $ (392,080,000) | $ (391,215,000)
Cumulative Effect, Period of Adoption, Adjustment |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Book value of long-term debt |  |  |  |  |  |  | 12,939,000 |  |
Stockholders' equity |  |  |  |  |  |  | (12,939,000) |  |
Cumulative Effect, Period of Adoption, Adjustment | Additional paid-in capital |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Stockholders' equity |  |  |  |  |  |  | (26,699,000) |  |
Cumulative Effect, Period of Adoption, Adjustment | Accumulated deficit |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Stockholders' equity |  |  |  |  |  |  | 13,760,000 |  |
Senior Notes |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Book value of long-term debt |  | $ 141,774,000 |  | $ 141,774,000 |  |  | $ 128,210,000 |  |
4.50% Exchangeable Senior Notes Due 2023 | Convertible Debt |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Debt instrument, face amount | $ 125,000 |  |  |  |  |  |  |  |
Debt instrument, interest rate, stated percentage | 4.50% |  |  |  |  |  |  |  |
Option to purchase aggregate principal amount, term | 30 days |  |  |  |  |  |  |  |
Option to increase aggregate principal amount | $ 18,750,000 |  |  |  |  |  |  |  |
Payments of debt issuance costs | 6,190,000 |  |  |  |  |  |  |  |
Proceeds from loans or conditional grants | $ 137,560,000 |  |  |  |  |  |  |  |
ADS, option price per share (in dollars per share) | $ / shares | $ 10.79 |  |  |  |  |  |  |  |
ADS premium percentage | 20.00% |  |  |  |  |  |  |  |
ADS purchased, price per share (in dollars per share) | $ / shares | $ 8.99 |  |  |  |  |  |  |  |
4.50% Exchangeable Senior Notes Due 2023 | Senior Notes |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Debt instrument, interest rate, stated percentage |  | 4.50% |  | 4.50% |  |  | 4.50% |  |
Debt Instrument, Redemption, Period One | 4.50% Exchangeable Senior Notes Due 2023 | Convertible Debt |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Number of business days | 5 days |  |  |  |  |  |  |  |
Consecutive business days | 5 days |  |  |  |  |  |  |  |
Percentage of product of the last reported sale price of the American Depositary Shares and the exchange rate on each such trading day | 98.00% |  |  |  |  |  |  |  |
Debt Instrument, Redemption, Period Two | 4.50% Exchangeable Senior Notes Due 2023 | Convertible Debt |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Scheduled threshold trading days | 35 days |  |  |  |  |  |  |  |
Threshold trading days | day | 95 |  |  |  |  |  |  |  |
Debt Instrument, Redemption, Period Three | 4.50% Exchangeable Senior Notes Due 2023 | Convertible Debt |  |  |  |  |  |  |  |  |
Schedule of Capitalization, Long-term Debt [Line Items] |  |  |  |  |  |  |  |  |
Threshold trading days | day | 20 |  |  |  |  |  |  |  |
Consecutive trading days | day | 30 |  |  |  |  |  |  |  |
Threshold percentage of stock price trigger | 130.00% |  |  |  |  |  |  |  |

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