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Disposition of the Hospital Business - Unaudited Pro Forma Condensed Combined Statement of Income (Loss) (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Error Corrections and Prior Period Adjustments Restatement [Line Items] |  |  |
Product sales | $ 0 | $ 22,334,000 | $ 59,215,000
Total operating expense | 85,546,000 | 16,519,000 | 83,327,000
Operating income (loss) | (85,546,000) | 5,815,000 | (24,112,000)
Cost of products | 0 | 5,742,000 | 12,125,000
Research and development expenses | 17,104,000 | 20,442,000 | 32,917,000
Selling, general and administrative expenses | 68,495,000 | 32,405,000 | 30,183,000
Intangible asset amortization | 0 | 406,000 | 816,000
Changes in fair value of contingent consideration | 0 | 3,327,000 | 845,000
Other expense - changes in fair value of contingent consideration payable | $ 0 | 435,000 | 378,000
Pro Forma |  |  |
Error Corrections and Prior Period Adjustments Restatement [Line Items] |  |  |
Product sales |  | 159,000 | (58,000)
Total operating expense |  | 8,127,000 | 67,235,000
Operating income (loss) |  | (7,968,000) | (67,293,000)
Loss before income taxes |  | (18,430,000) | (81,385,000)
As Reported |  |  |
Error Corrections and Prior Period Adjustments Restatement [Line Items] |  |  |
Product sales |  | 22,334,000 | 59,215,000
Total operating expense |  | 16,519,000 | 83,327,000
Operating income (loss) |  | 5,815,000 | (24,112,000)
Loss before income taxes |  | (5,082,000) | (38,582,000)
Pro Forma Adjustments | Pro Forma |  |  |
Error Corrections and Prior Period Adjustments Restatement [Line Items] |  |  |
Product sales |  | (22,175,000) | (59,273,000)
Total operating expense |  | (8,392,000) | (16,092,000)
Operating income (loss) |  | (13,783,000) | (43,181,000)
Loss before income taxes |  | (13,348,000) | (42,803,000)
Pro Forma Adjustments | Pro Forma | Disposal Group, Disposed of by Sale, Not Discontinued Operations |  |  |
Error Corrections and Prior Period Adjustments Restatement [Line Items] |  |  |
Cost of products |  | 3,540,000 | 11,368,000
Research and development expenses |  | 322,000 | 1,960,000
Selling, general and administrative expenses |  | 797,000 | 1,102,000
Intangible asset amortization |  | 406,000 | 816,000
Changes in fair value of contingent consideration |  | 3,327,000 | 845,000
Other expense - changes in fair value of contingent consideration payable |  | $ 435,000 | $ 378,000

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