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Disposition of the Hospital Business - Unaudited Pro Forma Condensed Combined Statement of Income (Loss) (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Error Corrections and Prior Period Adjustments Restatement [Line Items]      
Product sales $ 0 $ 22,334,000 $ 59,215,000
Total operating expense 85,546,000 16,519,000 83,327,000
Operating income (loss) (85,546,000) 5,815,000 (24,112,000)
Cost of products 0 5,742,000 12,125,000
Research and development expenses 17,104,000 20,442,000 32,917,000
Selling, general and administrative expenses 68,495,000 32,405,000 30,183,000
Intangible asset amortization 0 406,000 816,000
Changes in fair value of contingent consideration 0 3,327,000 845,000
Other expense - changes in fair value of contingent consideration payable $ 0 435,000 378,000
Pro Forma      
Error Corrections and Prior Period Adjustments Restatement [Line Items]      
Product sales   159,000 (58,000)
Total operating expense   8,127,000 67,235,000
Operating income (loss)   (7,968,000) (67,293,000)
Loss before income taxes   (18,430,000) (81,385,000)
As Reported      
Error Corrections and Prior Period Adjustments Restatement [Line Items]      
Product sales   22,334,000 59,215,000
Total operating expense   16,519,000 83,327,000
Operating income (loss)   5,815,000 (24,112,000)
Loss before income taxes   (5,082,000) (38,582,000)
Pro Forma Adjustments | Pro Forma      
Error Corrections and Prior Period Adjustments Restatement [Line Items]      
Product sales   (22,175,000) (59,273,000)
Total operating expense   (8,392,000) (16,092,000)
Operating income (loss)   (13,783,000) (43,181,000)
Loss before income taxes   (13,348,000) (42,803,000)
Pro Forma Adjustments | Pro Forma | Disposal Group, Disposed of by Sale, Not Discontinued Operations      
Error Corrections and Prior Period Adjustments Restatement [Line Items]      
Cost of products   3,540,000 11,368,000
Research and development expenses   322,000 1,960,000
Selling, general and administrative expenses   797,000 1,102,000
Intangible asset amortization   406,000 816,000
Changes in fair value of contingent consideration   3,327,000 845,000
Other expense - changes in fair value of contingent consideration payable   $ 435,000 $ 378,000