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Share-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs
Compensation expense included in the Company’s consolidated statements of (loss) income for all share-based compensation arrangements was as follows for the periods ended December 31, 2021, 2020 and 2019, respectively:

Share-based Compensation Expense:202120202019
Research and development $758 $139 $429 
Selling, general and administrative 8,114 3,281 2,154 
Restructuring costs— (421)(2,064)
Total share-based compensation expense$8,872 $2,999 $519 
Schedule of Share Based Payment Award Stock Options and Warrant Grants Valuation Assumptions
The weighted-average assumptions under the Black-Scholes option-pricing model for stock option grants as of December 31, 2021, 2020 and 2019, are as follows:   
Stock Option Assumptions: 202120202019
Stock option grants:   
Expected term (years)6.206.086.25
Expected volatility73.91 %75.76 %56.48 %
Risk-free interest rate1.10 %0.72 %2.52 %
Expected dividend yield— — — 
Schedule of Share-based Compensation, Stock Options, Activity
A summary of the combined stock option activity and other data for the Company’s stock option plans for the year ended December 31, 2021 is as follows:   
 Stock Option Activity and Other Data: Number of Stock
Options
Weighted Average
Exercise Price per Share
Weighted Average
Remaining
Contractual Life
Aggregate
Intrinsic Value
Stock options outstanding, January 1, 2021
5,898 $7.02   
Granted2,857 8.20   
Exercised(48)3.54   
Forfeited(234)7.13   
Expired(70)12.62 
Stock options outstanding, December 31, 2021
8,403 $7.39 7.83 years$12,204 
Stock options exercisable, December 31, 2021
3,256 $7.88 5.88 years$6,291 
Disclosure of Share-based Compensation Arrangements by Share-based Payment Award A summary of the Company’s restricted share awards as of December 31, 2021, and changes during the year then ended, is reflected in the table below. 
Restricted Share Activity and Other Data: Number of Restricted Share AwardsWeighted Average Grant Date
Fair Value
Non-vested restricted share awards outstanding, January 1, 2021
347 $5.87 
Granted99 8.22 
Vested(160)5.05 
Forfeited(12)7.08 
Non-vested restricted share awards outstanding, December 31, 2021
274 $7.14 
A summary of the Company’s performance share units awards as of December 31, 2021, and changes during the year then ended, is reflected in the table below.

Performance Unit Share Activity and Other DataNumber of Performance Share AwardsWeighted Average Grant Date
Fair Value
Non-vested performance share awards outstanding, January 1, 2021
257 $7.09 
Granted285 8.20 
Vested— — 
Forfeited(7)5.36 
Non-vested performance share awards outstanding, December 31, 2021
535 $7.71