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Company Operations by Product, Customer and Geographic Area - Revenue by Product (Details)	12 Months Ended
	Dec. 31, 2021 USD ($) segment	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Segment Reporting [Abstract]
Number of reportable segments | segment	1
Number of operating segments | segment	1
Product sales	$ 0	$ 22,334,000	$ 59,215,000
Segment Reporting Information [Line Items]
Product sales	$ 0	22,334,000	59,215,000
Bloxiverz
Segment Reporting [Abstract]
Product sales		2,201,000	7,479,000
Segment Reporting Information [Line Items]
Product sales		2,201,000	7,479,000
Vazculep
Segment Reporting [Abstract]
Product sales		10,429,000	33,152,000
Segment Reporting Information [Line Items]
Product sales		10,429,000	33,152,000
Akovaz
Segment Reporting [Abstract]
Product sales		9,545,000	18,642,000
Segment Reporting Information [Line Items]
Product sales		9,545,000	18,642,000
Other
Segment Reporting [Abstract]
Product sales		159,000	(58,000)
Segment Reporting Information [Line Items]
Product sales		$ 159,000	$ (58,000)

X

- Definition

Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.

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