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Company Operations by Product, Customer and Geographic Area - Revenue by Significant Customer (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Segment Reporting Information [Line Items]      
Product sales $ 0 $ 22,334,000 $ 59,215,000
McKesson Corporation      
Segment Reporting Information [Line Items]      
Product sales   5,758,000 14,900,000
Cardinal Health      
Segment Reporting Information [Line Items]      
Product sales   5,155,000 15,088,000
AmerisourceBergen      
Segment Reporting Information [Line Items]      
Product sales   3,155,000 12,059,000
QuVa Pharma      
Segment Reporting Information [Line Items]      
Product sales   3,117,000 3,252,000
Others      
Segment Reporting Information [Line Items]      
Product sales   $ 5,149,000 $ 13,916,000