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Long-Term Debt - Narrative (Details) $ / shares in Units, $ in Thousands							3 Months Ended		6 Months Ended
	Aug. 01, 2023 USD ($)	May 31, 2023 USD ($) $ / shares Rate shares	Apr. 04, 2023 USD ($)	Mar. 29, 2023 USD ($)	Apr. 05, 2022 USD ($)	Feb. 16, 2018 USD ($) $ / shares Rate	Jun. 30, 2023 USD ($) $ / shares	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($) day $ / shares	Jun. 30, 2022 USD ($)	Apr. 03, 2023 $ / shares	Mar. 31, 2023 USD ($)	Feb. 01, 2023 USD ($)	Dec. 31, 2022 USD ($) $ / shares	Nov. 04, 2022 USD ($)
Schedule of Capitalization, Long-term Debt [Line Items]
Interest expense, debt							$ 2,295	$ 3,506	$ 5,554	$ 5,523
Coupon interest expense							1,708	1,589	3,094	3,206
Amortization of debt discount and debt issuance costs							587	1,917	2,460	2,229
Payments of debt issuance costs									4,357	4,803
Change in fair value of October 2023 Notes conversion feature					$ 5,508			5,508
Increase in fair value of unseparated embedded conversion feature					5,508
ADSs, conversion ratio | Rate		11618.46%				9269.56%
Aggregate amount of conversion		$ 1,470
Loss on extinguishment of debt			$ 13,129				$ 13,129	$ 0	$ 13,129	$ 0
Ordinary shares, nominal value (in dollars per share) | $ / shares		$ 0.01					$ 0.01		$ 0.01		$ 0.01			$ 0.01
Number of ADSs delivered upon conversion (in shares) | shares		12,347
Quarterly net revenue target for royalty financing				$ 25,000
Subsequent Event
Schedule of Capitalization, Long-term Debt [Line Items]
Royalty financing	$ 30,000
Maximum
Schedule of Capitalization, Long-term Debt [Line Items]
Royalty financing				$ 75,000
4.50% Exchangeable Senior Notes Due 2023 | Convertible Debt
Schedule of Capitalization, Long-term Debt [Line Items]
Debt instrument, face amount					26,375	$ 125,000
Option to purchase aggregate principal amount, term						30 days
Option to increase aggregate principal amount						$ 18,750
Proceeds from loans or conditional grants						$ 137,560
Debt instrument, exchange amount					117,375
Debt instrument, repurchased face amount															$ 8,875
4.50% Exchangeable Senior Notes Due 2023 | Senior Notes
Schedule of Capitalization, Long-term Debt [Line Items]
Interest rate							4.50%		4.50%
Long-term debt							$ 0		$ 0				$ 17,500	$ 17,500
4.50% Exchangeable Senior Notes Due October 2023
Schedule of Capitalization, Long-term Debt [Line Items]
Interest rate												4.50%
4.50% Exchangeable Senior Notes Due October 2023 | Convertible Debt
Schedule of Capitalization, Long-term Debt [Line Items]
ADS, option price per share (in dollars per share) | $ / shares						$ 10.79
ADS premium percentage						20.00%
ADS shares purchase (in dollars per share) | $ / shares						$ 8.99
Threshold percentage of stock price trigger									130.00%
Threshold trading days | day									20
Consecutive trading days | day									30
4.50% Exchangeable Senior Notes Due October 2023 | Senior Notes
Schedule of Capitalization, Long-term Debt [Line Items]
Interest rate							4.50%		4.50%
Long-term debt			21,187				$ 21,187		$ 21,187			$ 117,375		$ 117,375
Payments of debt issuance costs					4,804
Debt exchanged			$ 96,188
4.50% Exchangeable Senior Notes Due October 2023 | Senior Notes | Third Party
Schedule of Capitalization, Long-term Debt [Line Items]
Payments of debt issuance costs					$ 5,450
April 2027 Notes
Schedule of Capitalization, Long-term Debt [Line Items]
Interest rate			6.00%
April 2027 Notes | Senior Notes
Schedule of Capitalization, Long-term Debt [Line Items]
Long-term debt			$ 106,268
Debt exchanged		$ 106,268
Aggregate amount of conversion			$ 106,268

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