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Summary of Significant Accounting Policies - Narrative (Details)
$ / shares in Units, shares in Thousands
 1 Months Ended 12 Months Ended
Aug. 01, 2023
USD ($)
Jun. 26, 2023
USD ($)
$ / shares
shares
Apr. 04, 2023
USD ($)
Apr. 03, 2023
USD ($)
$ / shares
shares
Mar. 29, 2023
USD ($)
Oct. 31, 2023
USD ($)
shares
Dec. 31, 2023
USD ($)
$ / shares
Dec. 31, 2022
USD ($)
$ / shares
Dec. 31, 2021
USD ($)
Mar. 31, 2023
USD ($)
Feb. 01, 2023
USD ($)
Class of Stock [Line Items]                      
Royalty financing, proceeds, maximum         $ 75,000,000            
Proceeds from royalty purchase agreement             $ 30,000,000 $ 0 $ 0    
Royalty financing, quarterly net revenue target         $ 25,000,000            
Debt converted, shares issued (in shares) | shares   12,347                  
Ordinary shares, nominal value (in usd per share) | $ / shares   $ 0.01   $ 0.01     $ 0.01 $ 0.01      
Net proceeds from shares issued       $ 134,151,000              
ADSs, conversion ratio   0.1161846                  
Debt converted   $ 1,470,000                  
Advertising expenses             $ 6,452,000 $ 0 0    
Goodwill impairment loss             $ 0 0      
Customer Concentration Risk | Accounts receivable | Three customers                      
Class of Stock [Line Items]                      
Concentration risk, percentage             100.00%        
Customer Concentration Risk | Accounts receivable | Caremark                      
Class of Stock [Line Items]                      
Concentration risk, percentage             52.00%        
Customer Concentration Risk | Accounts receivable | Accredo                      
Class of Stock [Line Items]                      
Concentration risk, percentage             28.00%        
Customer Concentration Risk | Accounts receivable | Optum                      
Class of Stock [Line Items]                      
Concentration risk, percentage             20.00%        
American Depositary Shares                      
Class of Stock [Line Items]                      
Debt converted, shares issued (in shares) | shares           408          
Ordinary shares                      
Class of Stock [Line Items]                      
Shares issued (in shares) | shares       12,205              
Series B Non-Voting Convertible Preferred Shares                      
Class of Stock [Line Items]                      
Shares issued (in shares) | shares       4,706              
Royalty Financing                      
Class of Stock [Line Items]                      
Proceeds from royalty purchase agreement $ 30,000,000           $ 30,000,000        
October 2023 Notes                      
Class of Stock [Line Items]                      
Debt repaid             $ 21,165,000 0 $ 0    
October 2023 Notes | Senior Notes                      
Class of Stock [Line Items]                      
Principal amount           $ 21,187,000   $ 117,375,000   $ 117,375,000 $ 17,500,000
Interest rate               4.50%   4.50%  
Debt exchanged     $ 96,188,000                
Debt repaid           $ 21,641,000          
April 2027 Notes | Senior Notes                      
Class of Stock [Line Items]                      
Principal amount     $ 106,268,000                
Interest rate     6.00%                
Debt converted     $ 106,268,000