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Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Taxes [Line Items]      
Income tax (benefit) provision $ (501) $ 26,025 $ (15,816)
Decrease in income tax provision 26,526    
Unrecognized tax benefits 3,035 3,143 2,483
Income tax penalties and interest expense 268 258 239
Income tax penalties and interest accrued 2,372 2,103 $ 1,777
Unremitted earnings 3,854    
Research tax credit receivable 1,654 3,480  
Orphan Drug tax credit      
Income Taxes [Line Items]      
Tax credit carryforwards 3,059    
Research and Development tax credits      
Income Taxes [Line Items]      
Tax credit carryforwards 1,005    
Ireland      
Income Taxes [Line Items]      
Net operating loss carryforwards 111,647    
Operating loss carryforwards, valuation allowance (decrease) 25,087    
Gross research tax credit 817 568  
U.S.      
Income Taxes [Line Items]      
Net operating loss carryforwards 212,426    
U.S. | 163(j) Credits      
Income Taxes [Line Items]      
Tax credit carryforwards 5,469    
France      
Income Taxes [Line Items]      
Gross research tax credit 837 $ 2,912  
FSC      
Income Taxes [Line Items]      
Net operating loss carryforwards 10,365    
U.S. Holdings      
Income Taxes [Line Items]      
Net operating loss carryforwards 195,595    
U.S. Holdings | State      
Income Taxes [Line Items]      
Net operating loss carryforwards $ 6,466