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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2024 | Mar. 31, 2024 | Sep. 30, 2023 | Mar. 31, 2023 | Sep. 30, 2024 | Sep. 30, 2023 | Dec. 31, 2023
Cash flows from operating activities: |  |  |  |  |  |  |
Net loss | $ (2,625) | $ (27,342) | $ (36,274) | $ (30,784) | $ (43,789) | $ (131,490) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |  |  |  |
Depreciation and amortization |  |  |  |  | 2,013 | 1,784 |
Amortization of debt discount and debt issuance costs |  |  |  |  | 0 | 2,796 |
Share-based compensation expense |  |  |  |  | 16,261 | 12,293 |
Loss on extinguishment of debt | 0 |  | 0 |  | 0 | 13,129 |
Other adjustments |  |  |  |  | (1,052) | (349) |
Net changes in assets and liabilities |  |  |  |  |  |  |
Accounts receivable |  |  |  |  | (24,999) | (6,239) |
Inventories |  |  |  |  | (5,255) | (5,286) |
Prepaid expenses and other current assets |  |  |  |  | (1,615) | (3,203) |
Accounts payable & other current liabilities |  |  |  |  | (3,516) | 3,837 |
Accrued expenses |  |  |  |  | 9,680 | 10,621 |
Other assets and liabilities |  |  |  |  | (2,508) | 1,625 |
Net cash used in operating activities |  |  |  |  | (54,780) | (100,482) |
Cash flows from investing activities: |  |  |  |  |  |  |
Proceeds from sales of marketable securities |  |  |  |  | 298,829 | 125,498 |
Purchases of marketable securities |  |  |  |  | (261,962) | (203,519) |
Net cash provided by (used in) investing activities |  |  |  |  | 36,867 | (78,021) |
Cash flows from financing activities: |  |  |  |  |  |  |
Payments for February 2023 Notes |  |  |  |  | 0 | (17,500) |
Payments for debt issuance costs |  |  |  |  | 0 | (4,357) |
Proceeds from royalty purchase agreement |  |  |  |  | 0 | 30,000 |
Proceeds from stock option exercises and employee share purchase plan |  |  |  |  | 5,840 | 2,241 |
Net cash provided by financing activities |  |  |  |  | 15,090 | 156,446 |
Effect of foreign currency exchange rate changes on cash and cash equivalents |  |  |  |  | 238 | (113) |
Net change in cash and cash equivalents |  |  |  |  | (2,585) | (22,170) |
Cash and cash equivalents at January 1, |  | $ 31,167 |  | $ 73,981 | 31,167 | 73,981 | $ 73,981
Cash and cash equivalents at September 30, | $ 28,582 |  | $ 51,811 |  | 28,582 | 51,811 | $ 31,167
Supplemental disclosures of cash flow information: |  |  |  |  |  |  |
Interest paid |  |  |  |  | 3,305 | 4,520 |
Public Offering |  |  |  |  |  |  |
Cash flows from financing activities: |  |  |  |  |  |  |
Proceeds from issuance of shares, net of issuance costs |  |  |  |  | 0 | 134,149 |
At-The-Market Offering Program |  |  |  |  |  |  |
Cash flows from financing activities: |  |  |  |  |  |  |
Proceeds from issuance of shares, net of issuance costs |  |  |  |  | $ 9,250 | $ 11,913 |

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