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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2024
Mar. 31, 2024
Sep. 30, 2023
Mar. 31, 2023
Sep. 30, 2024
Sep. 30, 2023
Dec. 31, 2023
Cash flows from operating activities:              
Net loss $ (2,625) $ (27,342) $ (36,274) $ (30,784) $ (43,789) $ (131,490)  
Adjustments to reconcile net loss to net cash used in operating activities:              
Depreciation and amortization         2,013 1,784  
Amortization of debt discount and debt issuance costs         0 2,796  
Share-based compensation expense         16,261 12,293  
Loss on extinguishment of debt 0   0   0 13,129  
Other adjustments         (1,052) (349)  
Net changes in assets and liabilities              
Accounts receivable         (24,999) (6,239)  
Inventories         (5,255) (5,286)  
Prepaid expenses and other current assets         (1,615) (3,203)  
Accounts payable & other current liabilities         (3,516) 3,837  
Accrued expenses         9,680 10,621  
Other assets and liabilities         (2,508) 1,625  
Net cash used in operating activities         (54,780) (100,482)  
Cash flows from investing activities:              
Proceeds from sales of marketable securities         298,829 125,498  
Purchases of marketable securities         (261,962) (203,519)  
Net cash provided by (used in) investing activities         36,867 (78,021)  
Cash flows from financing activities:              
Payments for February 2023 Notes         0 (17,500)  
Payments for debt issuance costs         0 (4,357)  
Proceeds from royalty purchase agreement         0 30,000  
Proceeds from stock option exercises and employee share purchase plan         5,840 2,241  
Net cash provided by financing activities         15,090 156,446  
Effect of foreign currency exchange rate changes on cash and cash equivalents         238 (113)  
Net change in cash and cash equivalents         (2,585) (22,170)  
Cash and cash equivalents at January 1,   $ 31,167   $ 73,981 31,167 73,981 $ 73,981
Cash and cash equivalents at September 30, $ 28,582   $ 51,811   28,582 51,811 $ 31,167
Supplemental disclosures of cash flow information:              
Interest paid         3,305 4,520  
Public Offering              
Cash flows from financing activities:              
Proceeds from issuance of shares, net of issuance costs         0 134,149  
At-The-Market Offering Program              
Cash flows from financing activities:              
Proceeds from issuance of shares, net of issuance costs         $ 9,250 $ 11,913