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Income Taxes - Additional Information (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Income Taxes [Line Items] |  |  |
Income tax benefit | $ 247 | $ 501 | $ (26,025)
Decrease in income tax benefit | 254 |  |
Decrease in unrecognized tax benefits is reasonably possible | 1,637 |  |
Unrecognized tax benefits | 2,724 | 3,035 | 3,143
Income tax penalties and interest expense | 56 | 268 | $ 258
Income tax penalties and interest accrued | 2,427 | 2,372 |
Unremitted earnings | 3,755 |  |
Research tax credit receivable | 587 | 1,654 |
Orphan Drug tax credit |  |  |
Income Taxes [Line Items] |  |  |
Tax credit carryforwards | 3,059 |  |
Research and Development tax credits |  |  |
Income Taxes [Line Items] |  |  |
Tax credit carryforwards | 1,036 |  |
Europe |  |  |
Income Taxes [Line Items] |  |  |
Net operating loss carryforwards | 71,588 |  |
Operating loss carryforwards, valuation allowance (decrease) | 5,137 |  |
Gross research tax credit |  | 817 |
U.S. |  |  |
Income Taxes [Line Items] |  |  |
Net operating loss carryforwards | 227,344 |  |
U.S. | 163(j) Credits |  |  |
Income Taxes [Line Items] |  |  |
Tax credit carryforwards | 5,809 |  |
France |  |  |
Income Taxes [Line Items] |  |  |
Gross research tax credit |  | $ 837 |
FSC |  |  |
Income Taxes [Line Items] |  |  |
Net operating loss carryforwards | 10,365 |  |
U.S. Holdings |  |  |
Income Taxes [Line Items] |  |  |
Net operating loss carryforwards | 212,637 |  |
U.S. Holdings | State |  |  |
Income Taxes [Line Items] |  |  |
Net operating loss carryforwards | $ 4,342 |  |

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