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Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Taxes [Line Items]      
Income tax benefit $ 247 $ 501 $ (26,025)
Decrease in income tax benefit 254    
Decrease in unrecognized tax benefits is reasonably possible 1,637    
Unrecognized tax benefits 2,724 3,035 3,143
Income tax penalties and interest expense 56 268 $ 258
Income tax penalties and interest accrued 2,427 2,372  
Unremitted earnings 3,755    
Research tax credit receivable 587 1,654  
Orphan Drug tax credit      
Income Taxes [Line Items]      
Tax credit carryforwards 3,059    
Research and Development tax credits      
Income Taxes [Line Items]      
Tax credit carryforwards 1,036    
Europe      
Income Taxes [Line Items]      
Net operating loss carryforwards 71,588    
Operating loss carryforwards, valuation allowance (decrease) 5,137    
Gross research tax credit   817  
U.S.      
Income Taxes [Line Items]      
Net operating loss carryforwards 227,344    
U.S. | 163(j) Credits      
Income Taxes [Line Items]      
Tax credit carryforwards 5,809    
France      
Income Taxes [Line Items]      
Gross research tax credit   $ 837  
FSC      
Income Taxes [Line Items]      
Net operating loss carryforwards 10,365    
U.S. Holdings      
Income Taxes [Line Items]      
Net operating loss carryforwards 212,637    
U.S. Holdings | State      
Income Taxes [Line Items]      
Net operating loss carryforwards $ 4,342