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CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS’ EQUITY - USD ($)
shares in Thousands, $ in Thousands
Total
Ordinary shares
Preferred shares
Additional paid-in capital
Accumulated deficit
Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2023   89,825 5,194      
Beginning balance at Dec. 31, 2023 $ 87,739 $ 898 $ 52 $ 855,452 $ (745,496) $ (23,167)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Net loss (27,342)       (27,342)  
Other comprehensive income (loss) (589)         (589)
Issuance of common stock, net of issuance costs (in shares)   640        
Issuance of common stock, net of issuance costs 9,250 $ 6   9,244    
Amortization of deferred issuance costs (3)     (3)    
Conversion of preferred stock into ordinary shares (in shares)   5,194 (5,194)      
Conversion of preferred stock into ordinary shares 0 $ 52 $ (52)      
Exercise of stock options (in shares)   390        
Exercise of stock options 3,356 $ 3   3,353    
Employee share purchase plan share issuance (in shares)   48        
Employee share purchase plan share issuance 584 $ 1   583    
Share-based compensation expense 5,389     5,389    
Ending balance (in shares) at Mar. 31, 2024   96,097 0      
Ending balance at Mar. 31, 2024 78,384 $ 960 $ 0 874,018 (772,838) (23,756)
Beginning balance (in shares) at Dec. 31, 2024   96,518 0      
Beginning balance at Dec. 31, 2024 73,848 $ 965 $ 0 891,791 (794,328) (24,580)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Net loss (4,920)       (4,920)  
Other comprehensive income (loss) 268         268
Exercise of stock options (in shares)   60        
Exercise of stock options 282 $ 1   281    
Vesting of restricted shares (in shares)   8        
Employee share purchase plan share issuance (in shares)   46        
Employee share purchase plan share issuance 409     408 1  
Share-based compensation expense 4,183     4,183    
Ending balance (in shares) at Mar. 31, 2025   96,632 0      
Ending balance at Mar. 31, 2025 $ 74,070 $ 966 $ 0 $ 896,663 $ (799,247) $ (24,312)