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CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
At-The-Market Offering Program
Ordinary shares
Ordinary shares
At-The-Market Offering Program
Preferred shares
Additional paid-in capital
Additional paid-in capital
At-The-Market Offering Program
Accumulated deficit
Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2023     89,825,000            
Beginning balance (in shares) at Dec. 31, 2023         5,194,000        
Beginning balance at Dec. 31, 2023 $ 87,739   $ 898   $ 52 $ 855,452   $ (745,496) $ (23,167)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net income (loss) (27,342)             (27,342)  
Other comprehensive income (loss) (589)               (589)
Issuance of common stock, net of issuance costs (in shares)       640,000          
Issuance of common stock, net of issuance costs   $ 9,250   $ 6     $ 9,244    
Amortization of deferred issuance costs (3)         (3)      
Conversion of preferred stock into ordinary shares (in shares)     5,194,000   (5,194,000)        
Conversion of preferred stock into ordinary shares 0   $ 52   $ (52)        
Exercise of stock options (in shares)     390,000            
Exercise of stock options 3,356   $ 3     3,353      
Employee share purchase plan share issuance (in shares)     48,000            
Employee share purchase plan share issuance 584   $ 1     583      
Share-based compensation expense 5,389         5,389      
Ending balance (in shares) at Mar. 31, 2024     96,097,000            
Ending balance (in shares) at Mar. 31, 2024         0        
Ending balance at Mar. 31, 2024 78,384   $ 960   $ 0 874,018   (772,838) (23,756)
Beginning balance (in shares) at Dec. 31, 2023     89,825,000            
Beginning balance (in shares) at Dec. 31, 2023         5,194,000        
Beginning balance at Dec. 31, 2023 87,739   $ 898   $ 52 855,452   (745,496) (23,167)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net income (loss) (41,164)                
Other comprehensive income (loss) (1,048)                
Ending balance (in shares) at Jun. 30, 2024     96,204,000            
Ending balance (in shares) at Jun. 30, 2024         0        
Ending balance at Jun. 30, 2024 70,288   $ 961   $ 0 880,202   (786,660) (24,215)
Beginning balance (in shares) at Mar. 31, 2024     96,097,000            
Beginning balance (in shares) at Mar. 31, 2024         0        
Beginning balance at Mar. 31, 2024 78,384   $ 960   $ 0 874,018   (772,838) (23,756)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net income (loss) (13,822)             (13,822)  
Other comprehensive income (loss) (459)               (459)
Exercise of stock options (in shares)     107,000            
Exercise of stock options 723   $ 1     722      
Share-based compensation expense 5,462         5,462      
Ending balance (in shares) at Jun. 30, 2024     96,204,000            
Ending balance (in shares) at Jun. 30, 2024         0        
Ending balance at Jun. 30, 2024 $ 70,288   $ 961   $ 0 880,202   (786,660) (24,215)
Beginning balance (in shares) at Dec. 31, 2024 96,518,000   96,518,000            
Beginning balance (in shares) at Dec. 31, 2024 0       0        
Beginning balance at Dec. 31, 2024 $ 73,848   $ 965   $ 0 891,791   (794,328) (24,580)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net income (loss) (4,920)             (4,920)  
Other comprehensive income (loss) 268               268
Exercise of stock options (in shares)     60,000            
Exercise of stock options 282   $ 1     281      
Vesting of restricted shares (in shares)     8,000            
Employee share purchase plan share issuance (in shares)     46,000            
Employee share purchase plan share issuance 409         408   1  
Share-based compensation expense 4,183         4,183      
Ending balance (in shares) at Mar. 31, 2025     96,632,000            
Ending balance (in shares) at Mar. 31, 2025         0        
Ending balance at Mar. 31, 2025 $ 74,070   $ 966   $ 0 896,663   (799,247) (24,312)
Beginning balance (in shares) at Dec. 31, 2024 96,518,000   96,518,000            
Beginning balance (in shares) at Dec. 31, 2024 0       0        
Beginning balance at Dec. 31, 2024 $ 73,848   $ 965   $ 0 891,791   (794,328) (24,580)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net income (loss) 4,745                
Other comprehensive income (loss) $ 934                
Ending balance (in shares) at Jun. 30, 2025 96,777,000   96,777,000            
Ending balance (in shares) at Jun. 30, 2025 0       0        
Ending balance at Jun. 30, 2025 $ 90,709   $ 967   $ 0 902,970   (789,582) (23,646)
Beginning balance (in shares) at Mar. 31, 2025     96,632,000            
Beginning balance (in shares) at Mar. 31, 2025         0        
Beginning balance at Mar. 31, 2025 74,070   $ 966   $ 0 896,663   (799,247) (24,312)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Net income (loss) 9,665             9,665  
Other comprehensive income (loss) 666               666
Exercise of stock options (in shares)     145,000            
Exercise of stock options 981   $ 1     980      
Share-based compensation expense $ 5,327         5,327      
Ending balance (in shares) at Jun. 30, 2025 96,777,000   96,777,000            
Ending balance (in shares) at Jun. 30, 2025 0       0        
Ending balance at Jun. 30, 2025 $ 90,709   $ 967   $ 0 $ 902,970   $ (789,582) $ (23,646)