    <SEC-DOCUMENT>0001193125-20-026787-index.html : 20200206
    <SEC-HEADER>0001193125-20-026787.hdr.sgml : 20200206
    <ACCEPTANCE-DATETIME>20200206161643
    ACCESSION NUMBER:		0001193125-20-026787
    CONFORMED SUBMISSION TYPE:	424B4
    PUBLIC DOCUMENT COUNT:		18
    FILED AS OF DATE:		20200206
    DATE AS OF CHANGE:		20200206

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Schrodinger, Inc.
    		CENTRAL INDEX KEY:			0001490978
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				954284541
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B4
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-235890
    		FILM NUMBER:		20582896

    	BUSINESS ADDRESS:
    		STREET 1:		120 WEST 45TH STREET
    		STREET 2:		17TH FLOOR
    		CITY:			NEW YORK
    		STATE:			NY
    		ZIP:			10036
    		BUSINESS PHONE:		503-299-1150

    	MAIL ADDRESS:
    		STREET 1:		120 WEST 45TH STREET
    		STREET 2:		17TH FLOOR
    		CITY:			NEW YORK
    		STATE:			NY
    		ZIP:			10036
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B4
    <SEQUENCE>1
    <FILENAME>d766269d424b4.htm
    <DESCRIPTION>424B4
    <TEXT>
    Document 1 - file: d766269d424b4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g766269g12k92.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g766269g12k92.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g766269g15l30.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g766269g15l30.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g766269g17h96.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g766269g17h96.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g766269g26l52.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g766269g26l52.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g766269g30a18.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g766269g30a18.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g766269g33i20.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g766269g33i20.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g766269g35g12.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g766269g35g12.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>g766269g40x35.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: g766269g40x35.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>g766269g45d14.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: g766269g45d14.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>g766269g46q96.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: g766269g46q96.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>g766269g46v24.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: g766269g46v24.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>g766269g50b43.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: g766269g50b43.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>g766269g58d70.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: g766269g58d70.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>g766269g59x67.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: g766269g59x67.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>g766269g66i18.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: g766269g66i18.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>g766269g73c53.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: g766269g73c53.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>g766269g95i46.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: g766269g95i46.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>