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Equity Investments - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 31, 2021
May 31, 2020
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Schedule of Equity Method Investments [Line Items]          
Equity investments gains (losses)     $ (1,781,000)    
Equity investments     52,931,000   $ 45,664,000
Distribution from equity investment     40,000    
Proceeds from sale of equity investments     $ 15,735,000    
Nimbus Therapeutics, LLC          
Schedule of Equity Method Investments [Line Items]          
Percentage of equity investment held on fully diluted basis     6.60%   6.90%
Equity investments gains (losses)     $ 0 $ (1,008,000)  
Equity investments     0   $ 0
Morphic Holding, Inc.          
Schedule of Equity Method Investments [Line Items]          
Equity investments gains (losses)     24,824,000 (2,071,000)  
Equity investments     52,837,000   28,013,000
Petra Pharma Corporation          
Schedule of Equity Method Investments [Line Items]          
Distribution from equity investment   $ 4,582,000      
Escrow payments receivable   $ 361,000      
Ravenna Therapeutics          
Schedule of Equity Method Investments [Line Items]          
Common shares received in connection with merger   2,676,191      
Carrying value of non-marketable equity securities     94,000   94,000
Relay Therapeutics, Inc          
Schedule of Equity Method Investments [Line Items]          
Equity investments gains (losses) $ (1,821,000)     $ 0  
Equity investments         $ 17,556,000
Proceeds from sale of equity investments $ 15,735,000        
Loss on sale of equity method investments     $ 1,821,000