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Income Taxes - Schedule of Tax Effects of Temporary Differences that Give Rise to Significant Portions of Deferred Income Tax Assets and Deferred Income Tax Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
--- | --- | --- | ---
Deferred income tax assets: |  |  |
Net operating loss carryforwards | $ 51,542 | $ 44,116 | $ 67,758
Capitalized research and development | 62,215 | 13,224 | 5,511
Accrued expenses | 37,544 | 71,676 | 43,362
Deferred revenue | 5,462 | 5,296 | 6,532
Lease liabilities | 27,551 | 32,491 | 28,952
Credits | 29,884 | 21,903 | 18,456
Gross deferred tax assets | 214,198 | 188,706 | 170,571
Less valuation allowance | (177,226) | (136,031) | (137,957)
Net deferred tax assets | 36,972 | 52,675 | 32,614
Deferred income tax liabilities: |  |  |
Unrealized gain on equity investments | (7,284) | (18,553) | (4,439)
Prepaid expenses | (652) | (1,554) | (1,435)
Depreciation and amortization | (29,036) | (32,568) | (26,740)
Net deferred income tax assets | $ 0 | $ 0 | $ 0

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