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Equity Investments (Details)			1 Months Ended				12 Months Ended
	Aug. 15, 2024 USD ($)	Feb. 07, 2023 $ / shares shares	Apr. 30, 2024 USD ($) shares	Apr. 30, 2022 USD ($) shares	Jul. 31, 2021 USD ($) shares	May 31, 2021 USD ($) shares	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)
Debt and Equity Securities, FV-NI [Line Items]
Mark-to-market gain (loss)							$ 5,683,000	$ 53,461,000	$ (18,084,000)
Cash payments to purchase of shares							3,072,000	4,125,000	600,000
Nimbus Therapeutics, LLC
Debt and Equity Securities, FV-NI [Line Items]
Non-marketable equity security							2,436,000	1,928,000
Unrealized (loss) gain							508,000	1,928,000	0
Realized gain								147,213,000
Morphic Holding, Inc.
Debt and Equity Securities, FV-NI [Line Items]
Proceeds from sale of equity securities	$ 47,588,000
Mark-to-market gain (loss)							23,474,000	1,778,000	(17,226,000)
Marketable securities							0	24,114,000
Ajax Therapeutics, Inc
Debt and Equity Securities, FV-NI [Line Items]
Non-marketable equity security							4,498,000	1,700,000
Mark-to-market gain (loss)							(202,000)	0	0
Structure Therapeutics
Debt and Equity Securities, FV-NI [Line Items]
Mark-to-market gain (loss)							(18,096,000)	49,755,000	$ (858,000)
Marketable securities							$ 36,202,000	$ 55,509,000
Series B preferred stock | Structure Therapeutics
Debt and Equity Securities, FV-NI [Line Items]
Number of preferred shares purchased | shares				148,210	494,035
Cash payments to purchase of shares				$ 600,000	$ 2,000,000
Conversion ratio		1
Series B preferred stock | Ajax Therapeutics, Inc
Debt and Equity Securities, FV-NI [Line Items]
Number of preferred shares purchased | shares						631,377
Cash payments to purchase of shares						$ 1,700,000
ADR | Structure Therapeutics
Debt and Equity Securities, FV-NI [Line Items]
Number of shares purchased | shares		275,000
Purchase price (in USD per share) | $ / shares		$ 15.00
Stock split, conversion ratio		3
Series C preferred stock | Ajax Therapeutics, Inc
Debt and Equity Securities, FV-NI [Line Items]
Number of preferred shares purchased | shares			1,416,450
Cash payments to purchase of shares			$ 3,000,000

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