<SEC-DOCUMENT>0001214659-26-005311.txt : 20260430
<SEC-HEADER>0001214659-26-005311.hdr.sgml : 20260430
<ACCEPTANCE-DATETIME>20260430060447
ACCESSION NUMBER:		0001214659-26-005311
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20260430
DATE AS OF CHANGE:		20260430

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Schrodinger, Inc.
		CENTRAL INDEX KEY:			0001490978
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				954284541
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91353
		FILM NUMBER:		26919731

	BUSINESS ADDRESS:	
		STREET 1:		1540 BROADWAY
		STREET 2:		24TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10036
		BUSINESS PHONE:		503-299-1150

	MAIL ADDRESS:	
		STREET 1:		1540 BROADWAY
		STREET 2:		24TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10036

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sumitomo Mitsui Trust Group, Inc.
		CENTRAL INDEX KEY:			0001475365
		STANDARD INDUSTRIAL CLASSIFICATION:	COMMERCIAL BANKS, NEC [6029]
		ORGANIZATION NAME:           	02 Finance
		EIN:				000000000
		STATE OF INCORPORATION:			M0

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		1-1, SHIBAKOEN, 1-CHOME
		CITY:			MINATO-KU, TOKYO
		STATE:			M0
		ZIP:			105-0011
		BUSINESS PHONE:		81-3-6256-6000

	MAIL ADDRESS:	
		STREET 1:		1-4-1, MARUNOUCHI
		CITY:			CHIYODA-KU, TOKYO
		STATE:			M0
		ZIP:			100-8233

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Sumitomo Mitsui Trust Holdings, Inc.
		DATE OF NAME CHANGE:	20110401

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Chuo Mitsui Trust Holdings, Inc.
		DATE OF NAME CHANGE:	20091027
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001214659-25-015322</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Sumitomo Mitsui Trust Group, Inc. -->
          <cik>0001475365</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Common stock, par value $0.01 per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>03/31/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001490978</issuerCik>
        <issuerName>Schrodinger, Inc.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>80810D103</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>1540 Broadway, 24th Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10036</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Sumitomo Mitsui Trust Group, Inc.</reportingPersonName>
      <memberGroup>a</memberGroup>
      <citizenshipOrOrganization>M0</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3190837.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3190837.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3190837.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>4.9</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <typeOfReportingPerson>FI</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Amova Asset Management Co., Ltd.</reportingPersonName>
      <memberGroup>a</memberGroup>
      <citizenshipOrOrganization>M0</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>3190837.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>3190837.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3190837.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>4.9</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
      <typeOfReportingPerson>FI</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Schrodinger, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>1540 Broadway, 24th Floor, New York, NY, 10036</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Sumitomo Mitsui Trust Group, Inc.
Amova Asset Management Co., Ltd.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>Sumitomo Mitsui Trust Group, Inc.:1-4-1 Marunouchi, Chiyoda-ku, Tokyo 100-8233, Japan
Amova Asset Management Co., Ltd.: Midtown Tower, 9-7-1 Akasaka, Minato-ku, Tokyo 107-6242, Japan</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Sumitomo Mitsui Trust Group, Inc.: Japan
Amova Asset Management Co., Ltd.: Japan</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>HC</typeOfPersonFiling>
        <typeOfPersonFiling>FI</typeOfPersonFiling>
        <typeOfPersonFiling>OO</typeOfPersonFiling>
        <otherTypeOfPersonFiling>Parent Holding Company</otherTypeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>3,190,837</amountBeneficiallyOwned>
        <classPercent>4.9</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>Sumitomo Mitsui Trust Group, Inc.: 0
Amova Asset Management Co., Ltd.: 0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>Sumitomo Mitsui Trust Group, Inc.: 3,190,837
Amova Asset Management Co., Ltd.:3,190,837</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>Sumitomo Mitsui Trust Group, Inc.: 0
Amova Asset Management Co., Ltd.: 0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>Sumitomo Mitsui Trust Group, Inc.: 3,190,837
Amova Asset Management Co., Ltd.: 3,190,837</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>N</notApplicableFlag>
        <subsidiaryIdentificationAndClassification>The securities being reported on by each of Sumitomo Mitsui Trust Group, Inc.(which is classified as a parent holding company or control person in accordance with ss. 240.13d-1(b)(1)(ii)(G) , as a non-U.S. institution in accordance with ss. 240.13d-1(b)(1)(ii)(J) and as Group, in accordance with ss. 240.13d-1(b)(1)(ii)(K)) and Amova Asset Management Co., Ltd. (which is classified as a parent holding company or control person in accordance with ss.240.13d-1(b)(1)(ii)(G) ,as an investment adviser in accordance with ss.240.13d-1(b)(1)(ii)(E) and as a non-U.S. institution in accordance with ss.240.13d-1(b)(1)(ii)(J)) ,as parent holding companies, are owned, or may be deemed to be beneficially owned, by their subsidiary Amova Asset Management Americas, Inc., (which is classified as an investment adviser in accordance with ss.240.13d-1(b)(1)(ii)(E)).</subsidiaryIdentificationAndClassification>
      </item7>
      <item8>
        <notApplicableFlag>N</notApplicableFlag>
        <identificationAndClassificationOfGroupMembers>The securities being reported on by each of Sumitomo Mitsui Trust Group, Inc.(which is classified as a parent holding company or control person in accordance with ss. 240.13d-1(b)(1)(ii)(G) , as a non-U.S. institution in accordance with ss. 240.13d-1(b)(1)(ii)(J) and as Group, in accordance with ss. 240.13d-1(b)(1)(ii)(K)) and Amova Asset Management Co., Ltd. (which is classified as a parent holding company or control person in accordance with ss.240.13d-1(b)(1)(ii)(G) ,as an investment adviser in accordance with ss.240.13d-1(b)(1)(ii)(E) and as a non-U.S. institution in accordance with ss.240.13d-1(b)(1)(ii)(J)) ,as parent holding companies, are owned, or may be deemed to be beneficially owned, by their subsidiary Amova Asset Management Americas, Inc., (which is classified as an investment adviser in accordance with ss.240.13d-1(b)(1)(ii)(E)).</identificationAndClassificationOfGroupMembers>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Sumitomo Mitsui Trust Group, Inc.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Hideaki Takamiya</signature>
        <title>Senior Manager of Risk Management Dept</title>
        <date>04/30/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Amova Asset Management Co., Ltd.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Atsushi Ohya</signature>
        <title>Head of Business Regulatory Compliance</title>
        <date>04/30/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
