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Liquidity, Going Concern and Management Plans (Details Narrative) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 9 Months Ended
Feb. 02, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Cash and Cash Equivalents, at Carrying Value   $ 393,130           $ 393,130   $ 134,942
Working capital deficit   181,600           181,600    
Accumulated Deficit   897,332           897,332   $ 626,456
Net loss   $ 105,865 $ 94,930 $ 70,186 $ 274,117 $ 73,604 $ 56,343 270,981 $ 404,064  
Proceeds from convertible debt               389,446 $ 3,003  
Proceeds from Issuance or Sale of Equity               13,100    
Sales Agreement [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Proceeds from Issuance of Common Stock               70,000    
[custom:DeductionOfCommissionAndExpenses]               $ 1,900    
Stock Issued During Period, Shares, New Issues               2,412,968    
[custom:WeightedAverageGrossSalePricePerShare-0]   $ 29.77           $ 29.77    
2026 Convertible Notes [Member]                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                    
Proceeds from convertible debt $ 402,500                  
Debt Instrument, Interest Rate, Stated Percentage 3.25%                  
Debt Instrument, Maturity Date, Description semi-annually in arrears on February 15 and August 15 of each year, beginning on August 15, 2021. The 2026 Convertible Notes will mature on February 15, 2026, unless earlier converted, redeemed, or repurchased.                  
Debt Instrument, Maturity Date Feb. 15, 2026                  
Proceeds from convertible debt net $ 389,400