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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2023 | Jun. 30, 2022
Cash flows from operating activities |  |
Net loss | $ (41,255) | $ (27,029)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Share-based compensation | 4,235 | 1,263
Depreciation | 144 | 129
Non-cash lease expense | 172 | 178
Amortization (accretion) of net investment premiums (discounts) | (1,990) | (147)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (1,387) | (990)
Other non-current assets | 22 |
Accounts payable | 122 | 12
Accrued expenses and other current liabilities | 2,922 | 3,027
Operating lease liabilities | (187) | (177)
Deferred tax liability |  | 121
Net cash used in operating activities | (37,202) | (23,613)
Cash flows from investing activities |  |
Purchases of short-term investments | (165,836) | (68,280)
Maturities of short-term investments | 48,300 | 12,500
Purchases of property and equipment | (191) | (12)
Net cash used in investing activities | (117,727) | (55,792)
Cash flows from financing activities |  |
Proceeds from issuance of common stock in initial public offering, net of underwriting discount and commissions | 172,296 |
Payments of deferred offering costs | (3,077) | (1,909)
Proceeds from issuance of Series B redeemable convertible preferred shares, net of issuance costs |  | 31,500
Repurchases of restricted shares |  | (6)
Proceeds from exercise of share options | 210 | 4
Net cash provided by financing activities | 169,429 | 29,589
Net change in cash and cash equivalents | 14,500 | (49,816)
Cash and cash equivalents, Beginning of the period | 26,091 | 105,305
Cash and cash equivalents, End of the period | 40,591 | 55,489
Supplemental disclosures of noncash investing and financing activities |  |
Conversion of redeemable convertible preferred shares into ordinary shares upon initial public offering | 199,975 |
Exchange of ordinary shares to non-voting ordinary shares | $ 1 |
Deferred offering costs included in accounts payable and accrued expenses and other current liabilities |  | 348
Accretion of redeemable convertible preferred shares to their redemption value |  | $ 1,515

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