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Summary of Significant Accounting Policies (Tables) | 9 Months Ended
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Sep. 30, 2025
Summary of Significant Accounting Policies |
Schedule of segment consolidated net loss, including significant segment expenses | The table below is a summary of the segment net loss, including significant segment expenses (in thousands):
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​ | ​ | THREE MONTHS ENDED | ​ | NINE MONTHS ENDED
​ | ​ | SEPTEMBER 30, | ​ | SEPTEMBER 30,
​ | ​ | 2025 |  | 2024 |  | 2025 |  | 2024
Operating expenses: | ​ | ​ |  | ​ | ​ |  | ​ | ​ |  | ​ | ​ |
Discovery research and development | ​ | $ | 24,602 | ​ | $ | 17,417 | ​ | $ | 72,633 | ​ | $ | 37,809
Clinical research and development | ​ | ​ | 28,647 | ​ | ​ | 11,811 | ​ | ​ | 68,953 | ​ | ​ | 29,507
Other research and development expenses | ​ | ​ | 5,740 | ​ | ​ | 3,370 | ​ | ​ | 14,980 | ​ | ​ | 8,011
General and administrative | ​ | ​ | 14,798 | ​ |  | 13,238 | ​ | ​ | 43,983 | ​ | ​ | 35,840
Total operating expenses | ​ |  | 73,787 | ​ |  | 45,836 | ​ |  | 200,549 | ​ |  | 111,167
Loss from operations | ​ |  | (73,787) | ​ |  | (45,836) | ​ |  | (200,549) | ​ |  | (111,167)
Interest and other income, net | ​ |  | 8,183 | ​ | ​ | 11,951 | ​ |  | 26,688 | ​ | ​ | 25,294
Loss before provision for income taxes | ​ |  | (65,604) | ​ |  | (33,885) | ​ |  | (173,861) | ​ |  | (85,873)
Provision for income taxes | ​ |  | 108 | ​ | ​ | 92 | ​ |  | 345 | ​ | ​ | 174
Segment net loss and net loss attributable to ordinary shareholders | ​ | $ | (65,712) | ​ | $ | (33,977) | ​ | $ | (174,206) | ​ | $ | (86,047)
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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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