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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Operating expenses:        
Research and development $ 58,989 $ 32,598 $ 156,566 $ 75,327
General and administrative 14,798 13,238 43,983 35,840
Total operating expenses 73,787 45,836 200,549 111,167
Loss from operations (73,787) (45,836) (200,549) (111,167)
Interest and other income, net 8,183 11,951 26,688 25,294
Loss before provision for income taxes (65,604) (33,885) (173,861) (85,873)
Provision for income taxes 108 92 345 174
Net loss attributable to ordinary shareholders $ (65,712) $ (33,977) $ (174,206) $ (86,047)
Net loss per share attributable to ordinary shareholders, basic $ (0.37) $ (0.2) $ (1) $ (0.56)
Net loss per share attributable to ordinary shareholders, diluted $ (0.37) $ (0.2) $ (1) $ (0.56)
Weighted-average ordinary shares used in computing net loss per share attributable to ordinary shareholders, basic 175,469 171,630 173,402 153,260
Weighted-average ordinary shares used in computing net loss per share attributable to ordinary shareholders, diluted 175,469 171,630 173,402 153,260
Other comprehensive gain (loss):        
Unrealized gain (loss) on investments, net $ 463 $ 3,326 $ (89) $ 2,318
Total other comprehensive gain (loss) 463 3,326 (89) 2,318
Comprehensive loss $ (65,249) $ (30,651) $ (174,295) $ (83,729)