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v3.22.1

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Cash flows used in operating activities: |  |
Net loss | $ (37,630) | $ (50,379)
Adjustments to reconcile net loss to net cash used in operating activities |  |
Depreciation and amortization | 687 | 688
Amortization of intangible assets | 151 | (272)
Share-based compensation expense | 7,023 | 7,821
Other, net | 1,514 | (2,111)
Net changes in operating assets and liabilities |  |
Accounts receivable | (4,986) | (1,187)
Inventories | (6,940) | (2,009)
Prepaid expenses and other current assets | 307 | 308
Non-current assets | 0 | 229
Accounts payable, accrued and other liabilities | (6,704) | (7,103)
Lease liabilities | (168) | 474
Net cash used in operating activities | (46,746) | (53,541)
Cash flows used in investing activities: |  |
Purchase of investments | (163,504) | (115,168)
Proceeds from investments | 110,566 | 60,940
Upfront lease payment | 0 | (11,838)
Purchase of long-lived assets | (79) | (136)
Additions to internal use-software implementation costs | 0 | (1,039)
Capitalized patent costs | 0 | (6)
Net cash used in investing activities | (53,017) | (67,247)
Cash flows from financing activities |  |
Proceeds from exercise of stock options | 405 | 4,999
Proceeds from exercise of warrants | 0 | 30
Cash provided by financing activities | 405 | 5,029
Net decrease in cash, cash equivalents and restricted cash | (99,358) | (115,759)
Cash, cash equivalents and restricted cash, beginning of period | 231,900 | 272,350
Cash, cash equivalents and restricted cash, end of period | 132,542 | 156,591
Supplemental cash flow information: |  |
Cash received for interest | 13 | 425
Cash paid for amounts included in the measurement of lease liabilities | (281) | (63)
Supplemental disclosure of noncash transactions |  |
Initial recognition of operating lease right-of-use asset | 0 | 5,804
Reconciliation of cash, cash equivalents and restricted cash to the condensed consolidated balance sheets |  |
Cash, cash equivalents | 131,636 | 156,591
Restricted cash | 906 | 0
Total cash, cash equivalents and restricted cash | $ 132,542 | $ 156,591

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- Definition Amount of income (expense) included in net income that results in no cash inflow (outflow), classified as other. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585 + Details
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- Definition The cash outflow associated with the development, modification or acquisition of software programs or applications for internal use (that is, not to be sold, leased or otherwise marketed to others) that qualify for capitalization. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585 + Details
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- Definition The cash outflow to acquire asset without physical form usually arising from contractual or other legal rights, excluding goodwill. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585 + Details
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- Definition The cash outflow for the purchase of receivables arising from the lease of real estate, equipment or other fixed assets for a specified time in exchange for payment, usually in the form of rent. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585 + Details
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- Definition Amount of cash outflow for purchase of marketable security. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=124260329&loc=d3e26853-111562 + Details
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- Definition Amount of cash outflow for the purchase of or improvements to tangible or intangible assets, used to produce goods or deliver services, classified as other. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3213-108585 + Details
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- Definition Interest received on loans and other debt instruments during the current period. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 16 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3337-108585 + Details
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- Definition Amount of increase in right-of-use asset obtained in exchange for operating lease liability. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 55 -Paragraph 53 -URI http://asc.fasb.org/extlink&oid=123414884&loc=SL77918982-209971 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 4 -Subparagraph (g)(2) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918686-209980 + Details
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