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Restructuring and Related Activities - Summary of Activity Related to the Restructuring Liabilities (Detail) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
Restructuring Cost and Reserve [Line Items] |  |  |  |
Beginning balance |  |  | $ 2,596 |
Accretion |  | $ 1,416 | 116 | $ 1,416
Provision |  |  | 28 |
Cash payments |  |  | (875) | $ (88)
Lease assignment to NeuBase |  |  | (136) |
Ending balance | $ 1,729 |  | 1,729 |
Lease-related exit costs |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Beginning balance | 1,795 |  | 2,584 |
Accretion | 31 |  | 116 |
Provision | 28 |  | 28 |
Cash payments | (125) |  | (863) |
Lease assignment to NeuBase |  |  | (136) |
Ending balance | $ 1,729 |  | 1,729 |
Employee termination |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Beginning balance |  |  | 12 |
Cash payments |  |  | $ (12) |

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- Definition Amount of cash payments made as the result of exit or disposal activities. Excludes payments associated with a discontinued operation or an asset retirement obligation. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b)(2) -URI http://asc.fasb.org/extlink&oid=6394359&loc=d3e17939-110869 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 17 -Subparagraph (f) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3367-108585 + Details
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