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Restructuring and Related Activities - Summary of Activity Related to the Restructuring Liabilities (Detail) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Restructuring Cost and Reserve [Line Items]
Beginning balance			$ 2,596
Accretion		$ 1,416	116	$ 1,416
Provision			28
Cash payments			(875)	$ (88)
Lease assignment to NeuBase			(136)
Ending balance	$ 1,729		1,729
Lease-related exit costs
Restructuring Cost and Reserve [Line Items]
Beginning balance	1,795		2,584
Accretion	31		116
Provision	28		28
Cash payments	(125)		(863)
Lease assignment to NeuBase			(136)
Ending balance	$ 1,729		1,729
Employee termination
Restructuring Cost and Reserve [Line Items]
Beginning balance			12
Cash payments			$ (12)