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Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023
Cash flows from operating activities |  |
Net Income (Loss) | $ (152,148) | $ (95,990)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 105 | 21
Accretion of discount and amortization of premium on purchase of debt securities | (8,972) | (4,433)
Accretion of loan exit fee and amortization of loan costs | 810 | 326
Reduction in the carrying amount of operating lease right-of-use assets | 2,064 | 2,224
Stock-based compensation | 20,802 | 11,493
Changes in operating assets and liabilities: |  |
Prepaid expense and other current assets | 981 | 173
Other assets | 351 | (262)
Accounts payable | (3,453) | (873)
Accrued and other liabilities | 7,188 | (2,215)
Operating lease liabilities | (2,407) | (2,645)
Net cash used in operating activities | (134,679) | (92,181)
Cash flows from investing activities |  |
Purchase of property and equipment | (972) | (63)
Purchase of marketable securities | (703,015) | (224,930)
Proceeds from maturities of marketable securities | 274,958 | 176,019
Proceeds from sale of marketable securities | 4,000 | 9,543
Net cash used in investing activities | (425,029) | (39,431)
Cash flows from financing activities |  |
Proceeds from exercise of stock options and employee stock purchase plan | 13,413 | 1,056
Proceeds from short swing settlement | 37 | 0
Proceeds from borrowings, net of costs | 0 | 24,741
Repurchase of common stock | (13) | 0
Proceeds from issuance of common stock in follow-on offerings | 632,500 | 115,000
Payment of issuance costs and underwriting fees related to follow-on offerings | (39,264) | (7,256)
Net cash provided by financing activities | 606,673 | 133,541
Net increase in cash and cash equivalents | 46,965 | 1,929
Cash and cash equivalents, beginning of year | 45,681 | 43,752
Cash and cash equivalents, end of year | 92,646 | 45,681
Supplemental disclosure of cash flow information |  |
Cash paid for interest expense | $ 6,652 | $ 3,352

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- Definition Amount of cash outflow for purchase of marketable security. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 320 -SubTopic 10 -Name Accounting Standards Codification -Section 45 -Paragraph 11 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481830/320-10-45-11 + Details
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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 230 -SubTopic 10 -Name Accounting Standards Codification -Section 45 -Paragraph 13 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-13 + Details
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- Definition Amount of cash inflow from issuance of shares under share-based payment arrangement. Includes, but is not limited to, option exercised. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 14 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-14 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2A -Subparagraph (a) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2A + Details
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- Definition The cash inflow associated with the aggregate amount received by the entity through sale or maturity of marketable securities (held-to-maturity or available-for-sale) during the period. + References No definition available. + Details
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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-28 + Details
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- Definition Accretion of discount and amortization of premium on purchase of debt securities. + References No definition available. + Details
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- Definition Payments of stock issuance costs on follow on offering. + References No definition available. + Details
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