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Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Cash Flows from Operating Activities |  |  |
Net income (loss) | $ (31,978) | $ (66,940) | $ (42,263)
Adjustments to reconcile net income (loss) to net cash provided by operating activities: |  |  |
Depreciation and amortization | 39,850 | 24,573 | 18,425
Deferred income taxes | 2,648 | (11,330) | (12,264)
Share-based compensation expense | 17,986 | 18,813 | 13,130
Provision (recovery) for bad debts | 43 | (1,814) | 1,946
Asset impairment | 126 | 58,170 | 1,220
Gain on sale of lab tools | (1,261) | (1,549) | (767)
Gain on cumulative translation adjustment |  | (3,142) |
Change in contingent consideration |  | (29,368) | 829
Changes in operating assets and liabilities: |  |  |
Accounts receivable | 10,715 | (25,390) | 36,898
Inventory and deferred cost of sales | (12,312) | 6,513 | 2,753
Prepaid expenses and other current assets | (39) | (2,245) | 842
Accounts payable and accrued expenses | 9,470 | (5,534) | 7,542
Customer deposits and deferred revenue | (20,738) | 55,536 | (17,329)
Income taxes receivable and payable, net | 759 | 20,279 | (12,734)
Other, net | 520 | 5,497 | 2,499
Net cash provided by operating activities | 15,789 | 42,069 | 727
Cash Flows from Investing Activities |  |  |
Acquisitions of businesses, net of cash acquired | (68) | (144,069) | (71,488)
Capital expenditures | (13,887) | (15,588) | (9,174)
Proceeds from the liquidation of investments | 88,647 | 318,276 | 499,645
Payments for purchases of investments | (84,244) | (157,737) | (589,099)
Payment for purchase of cost method investment | (1,594) | (2,388) | (2,391)
Proceeds from sale of lab tools | 3,068 | 9,259 | 4,440
Other | 1,000 | 350 | 11
Net cash provided by (used in) investing activities | (7,078) | 8,103 | (168,056)
Cash Flows from Financing Activities |  |  |
Proceeds from stock option exercises | 2,233 | 12,056 | 2,199
Restricted stock tax withholdings | (3,215) | (2,075) | (2,696)
Contingent consideration payments |  |  | 5,000
Purchases of common stock | (8,907) |  |
Repayments of long-term debt | (314) | (290) | (269)
Net cash provided by (used in) financing activities | (10,203) | 9,691 | (5,766)
Effect of exchange rate changes on cash and cash equivalents | (87) | 149 | (663)
Net increase (decrease) in cash and cash equivalents | (1,579) | 60,012 | (173,758)
Cash and cash equivalents - beginning of period | 270,811 | 210,799 | 384,557
Cash and cash equivalents - end of period | 269,232 | 270,811 | 210,799
Supplemental Disclosure of Cash Flow Information |  |  |
Interest paid | 485 | 159 | 357
Income taxes paid | $ 7,091 | $ 3,320 | $ 8,001

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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3213-108585 + Details
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- Definition The cash inflow associated with the sale or maturity (principal being due) of securities not classified as either held-to-maturity securities or trading securities which are classified as available-for-sale securities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3179-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=6871852&loc=d3e26853-111562 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 + Details
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- Definition The cash inflow associated with the amount received from holders exercising their stock options. This item inherently excludes any excess tax benefit, which the entity may have realized and reported separately. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (j) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3255-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition Amount of expense related to write-down of receivables to the amount expected to be collected. Includes, but is not limited to, accounts receivable and notes receivable. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.5) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 5 -Article 5 + Details
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- Definition The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3291-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
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- Definition Represents the amount of contingent consideration in a business combination earned and paid during the period. + References No definition available. + Details
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- Definition The noncash component of income tax expense for the period representing the increase (decrease) in the entity's deferred tax assets and liabilities pertaining to continuing operations. + References No definition available. + Details
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- Definition The cash inflow from the sale of assets used in the investing activities of the entity's discontinued operations during the period. + References No definition available. + Details
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