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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Cash Flows from Operating Activities      
Net income (loss) $ (31,978) $ (66,940) $ (42,263)
Adjustments to reconcile net income (loss) to net cash provided by operating activities:      
Depreciation and amortization 39,850 24,573 18,425
Deferred income taxes 2,648 (11,330) (12,264)
Share-based compensation expense 17,986 18,813 13,130
Provision (recovery) for bad debts 43 (1,814) 1,946
Asset impairment 126 58,170 1,220
Gain on sale of lab tools (1,261) (1,549) (767)
Gain on cumulative translation adjustment   (3,142)  
Change in contingent consideration   (29,368) 829
Changes in operating assets and liabilities:      
Accounts receivable 10,715 (25,390) 36,898
Inventory and deferred cost of sales (12,312) 6,513 2,753
Prepaid expenses and other current assets (39) (2,245) 842
Accounts payable and accrued expenses 9,470 (5,534) 7,542
Customer deposits and deferred revenue (20,738) 55,536 (17,329)
Income taxes receivable and payable, net 759 20,279 (12,734)
Other, net 520 5,497 2,499
Net cash provided by operating activities 15,789 42,069 727
Cash Flows from Investing Activities      
Acquisitions of businesses, net of cash acquired (68) (144,069) (71,488)
Capital expenditures (13,887) (15,588) (9,174)
Proceeds from the liquidation of investments 88,647 318,276 499,645
Payments for purchases of investments (84,244) (157,737) (589,099)
Payment for purchase of cost method investment (1,594) (2,388) (2,391)
Proceeds from sale of lab tools 3,068 9,259 4,440
Other 1,000 350 11
Net cash provided by (used in) investing activities (7,078) 8,103 (168,056)
Cash Flows from Financing Activities      
Proceeds from stock option exercises 2,233 12,056 2,199
Restricted stock tax withholdings (3,215) (2,075) (2,696)
Contingent consideration payments     5,000
Purchases of common stock (8,907)    
Repayments of long-term debt (314) (290) (269)
Net cash provided by (used in) financing activities (10,203) 9,691 (5,766)
Effect of exchange rate changes on cash and cash equivalents (87) 149 (663)
Net increase (decrease) in cash and cash equivalents (1,579) 60,012 (173,758)
Cash and cash equivalents - beginning of period 270,811 210,799 384,557
Cash and cash equivalents - end of period 269,232 270,811 210,799
Supplemental Disclosure of Cash Flow Information      
Interest paid 485 159 357
Income taxes paid $ 7,091 $ 3,320 $ 8,001