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Stock Plans - Plans and Awards (Details) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2013
Dec. 31, 2015
Dec. 31, 2014
Inducement Plan        
Stock plans disclosures        
Common stock available for issuance (in shares)   0    
2010 Stock Incentive Plan        
Stock plans disclosures        
Maximum number of shares authorized to be issued 10,600,000      
Shares reserved for future issuance        
Total shares reserved 6,300,000      
2016 Employee Stock Purchase Plan        
Stock plans disclosures        
Common stock available for issuance (in shares) 750,000      
Share price (as a percent) 85.00%      
Shares reserved for future issuance        
Total shares reserved 700,000      
Stock option Awards        
Stock plans disclosures        
Number of options outstanding (in shares) 1,576,000 2,598,000 2,064,000 2,391,000
Stock option Awards | Inducement Plan        
Stock plans disclosures        
Vesting period   3 years    
Expiration term   10 years    
Number of options outstanding (in shares) 77,500      
Awards granted (in shares)   124,500    
Stock option Awards | 2010 Stock Incentive Plan        
Stock plans disclosures        
Vesting period 3 years      
Number of options outstanding (in shares) 1,500,000      
Stock option Awards | 2010 Stock Incentive Plan | Minimum        
Stock plans disclosures        
Expiration term 7 years      
Stock option Awards | 2010 Stock Incentive Plan | Maximum        
Stock plans disclosures        
Expiration term 10 years      
Restricted Stock Awards and Restricted Stock Units | 2010 Stock Incentive Plan | Minimum        
Stock plans disclosures        
Vesting period 1 year      
Restricted Stock Awards and Restricted Stock Units | 2010 Stock Incentive Plan | Maximum        
Stock plans disclosures        
Vesting period 5 years      
Restricted stock units | Inducement Plan        
Stock plans disclosures        
Number of awards other than options outstanding (in shares) 5,200      
Awards granted (in shares)   87,000    
Restricted stock units | Inducement Plan | Minimum        
Stock plans disclosures        
Vesting period   2 years    
Restricted stock units | Inducement Plan | Maximum        
Stock plans disclosures        
Vesting period   4 years    
RSUs and PSUs | 2010 Stock Incentive Plan        
Stock plans disclosures        
Number of awards other than options outstanding (in shares) 600,000