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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Cash Flows from Operating Activities      
Net income (loss) $ (44,793) $ (122,210) $ (31,978)
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities:      
Depreciation and amortization 50,095 32,650 39,850
Non-cash interest expense 10,446    
Deferred income taxes (33,875) 940 2,648
Share-based compensation expense 24,396 15,741 17,986
Asset impairment 1,139 69,520 126
Provision for bad debts 99 171 43
Gain on sale of lab tools     (1,261)
Gain on cumulative translation adjustment   (430)  
Changes in operating assets and liabilities:      
Accounts receivable 4,520 (8,667) 10,715
Inventories and deferred cost of sales 6,336 (5,389) (12,312)
Prepaid expenses and other current assets (10,204) 6,726 (39)
Accounts payable and accrued expenses 12,197 (24,202) 9,470
Customer deposits and deferred revenue 19,096 8,807 (20,738)
Income taxes receivable and payable, net 775 547 759
Long-term income tax liability (4,877)    
Other, net (1,204) 1,952 520
Net cash provided by (used in) operating activities 34,146 (23,844) 15,789
Cash Flows from Investing Activities      
Acquisitions of businesses, net of cash acquired (401,828)   (68)
Capital expenditures (24,272) (11,479) (13,887)
Proceeds from the sale of investments 348,927 152,301 88,647
Payments for purchases of investments (282,947) (103,394) (85,838)
Proceeds from held for sale assets 2,284 9,512 3,068
Other   (230) 1,000
Net cash provided by (used in) investing activities (357,836) 46,710 (7,078)
Cash Flows from Financing Activities      
Proceeds (net of tax withholdings) from option exercises and employee stock purchase plan 2,992 1,656 2,233
Restricted stock tax withholdings (8,741) (2,601) (3,215)
Purchases of common stock (2,869) (13,349) (8,907)
Proceeds from long-term debt borrowings 335,752    
Principal payments on long-term debt (1,194) (340) (314)
Net cash provided by (used in) financing activities 325,940 (14,634) (10,203)
Effect of exchange rate changes on cash and cash equivalents 42 (20) (87)
Net increase (decrease) in cash and cash equivalents 2,292 8,212 (1,579)
Cash and cash equivalents - beginning of period 277,444 269,232 270,811
Cash and cash equivalents - end of period 279,736 277,444 269,232
Supplemental Disclosure of Cash Flow Information      
Interest paid 4,675 225 485
Income taxes paid 1,939 1,669 $ 7,091
Non-cash operating and financing activities      
Net transfer of inventory to property, plant and equipment $ (97) $ 1,827