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Share-based Compensation (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Share-based compensation        
Non-cash share based compensation $ 2,942 $ 3,783 $ 9,562 $ 11,528
Cost of sales        
Share-based compensation        
Non-cash share based compensation 389 383 1,384 1,448
Research and development        
Share-based compensation        
Non-cash share based compensation 674 756 2,161 2,531
Selling, general and administrative        
Share-based compensation        
Non-cash share based compensation $ 1,879 $ 2,644 $ 6,017 $ 7,549
Restricted stock awards | Minimum        
Share-based compensation        
Expiration term     1 year  
Restricted stock awards | Maximum        
Share-based compensation        
Expiration term     5 years  
Stock options        
Number of Shares        
Outstanding at the beginning of the period (in shares)     1,119  
Expired or forfeited (in shares)     (339)  
Outstanding at the end of the period (in shares) 780   780  
Weighted Average Exercise Price        
Outstanding at the beginning of the period (in dollars per share)     $ 34.88  
Expired or forfeited (in dollars per share)     33.94  
Outstanding at the end of the period (in dollars per share) $ 35.28   $ 35.28  
Non-vested restricted shares and performance shares        
Number of Shares        
Outstanding at the beginning of the period (in shares)     2,257  
Granted (in shares)     1,006  
Performance award adjustments (in shares)     (51)  
Vested (in shares)     (775)  
Forfeited (in shares)     (366)  
Outstanding at the end of the period (in shares) 2,071   2,071  
Weighted Average Grant Date Fair Value        
Outstanding at the beginning of the period (in dollars per share)     $ 16.20  
Granted (in dollars per share)     9.40  
Performance award adjustments (in dollars per share)     30.94  
Vested (in dollars per share)     15.97  
Forfeited (in dollars per share)     15.38  
Outstanding at the end of the period (in dollars per share) $ 12.76   $ 12.76